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• W4289779609 abstract "Hypersampones A-C (1-3), three unprecedented nor-polycyclic polyprenylated acylphloroglucinols (PPAPs), were isolated from Hypericum sampsonii. These compounds represent the first nor-PPAPs with an unexpected tetracyclic 6/5/5/6 ring system. Their structures were assigned through the analysis of detailed spectroscopic data, X-ray crystallography, and electronic circular dichroism calculations. Compound 1 significantly inhibited the accumulation of lipid in an oleic acid-treated HepG2 cell model by suppressing the protein expression of FAS and ACACA at 5 μM." @default.
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• W4289779609 date "2022-08-04" @default.
• W4289779609 modified "2023-10-16" @default.
• W4289779609 title "Hypersampones A–C, Three Nor-Polycyclic Polyprenylated Acylphloroglucinols with Lipid-Lowering Activity from <i>Hypericum sampsonii</i>" @default.
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• W4289779609 doi "https://doi.org/10.1021/acs.orglett.2c02240" @default.
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