Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311471183> ?p ?o ?g. }
- W4311471183 abstract "Abstract Textiles containing interposed layers of polyethylene oxide (PEO)‐fibrinogen and PEO‐thrombin fibers are explored as biomaterials for hemostasis. The PEO‐fibrinogen and PEO‐thrombin fibers are formed by contact drawing, an approach that uses an entangled polymer solution and a pin array to form fibers by extension of liquid bridges. The interposition of the PEO‐fibrinogen and PEO‐thrombin fibers results in polymerization of a fibrin hydrogel mesh once the textile is hydrated. This fibrin hydrogel mesh displays the expected bands and diffraction peaks by Fourier‐transform infrared spectromicroscopy and X‐ray diffraction, respectively. The functionality of the hemostatic textiles formed from the interposed PEO‐fibrinogen and PEO‐thrombin fibers is demonstrated by analyzing human blood hemolysis, complement activation, protein adsorption, and platelet and leukocyte adhesion, indicating compatibility with human blood (hemolysis ratio <5%), with minimal inflammatory response (levels of terminal complement complex equivalent to plasma). The cytocompatibility and potential for cell remodeling of the fibrin hydrogel mesh formed by this process is evaluated with human dermal fibroblasts and human keratinocytes and it is found that both cell types attach and grow on the fibrin mesh. Finally, a whole blood clotting time of less than 30 s suggests a potential use of this material in hemorrhage control." @default.
- W4311471183 created "2022-12-26" @default.
- W4311471183 creator A5000232732 @default.
- W4311471183 creator A5049260008 @default.
- W4311471183 creator A5055765566 @default.
- W4311471183 creator A5059211017 @default.
- W4311471183 date "2022-12-04" @default.
- W4311471183 modified "2023-10-12" @default.
- W4311471183 title "Nonwoven Hemostatic Dressings Formed by Contact Drawing of Interposed Polyethylene Oxide (PEO)‐Fibrinogen and PEO‐Thrombin Microfibers" @default.
- W4311471183 cites W1121403891 @default.
- W4311471183 cites W1562726151 @default.
- W4311471183 cites W1724366065 @default.
- W4311471183 cites W1970690188 @default.
- W4311471183 cites W1980100440 @default.
- W4311471183 cites W1996967454 @default.
- W4311471183 cites W2006293762 @default.
- W4311471183 cites W2008360623 @default.
- W4311471183 cites W2010319438 @default.
- W4311471183 cites W2015332717 @default.
- W4311471183 cites W2021623392 @default.
- W4311471183 cites W2027221209 @default.
- W4311471183 cites W2036059912 @default.
- W4311471183 cites W2036521370 @default.
- W4311471183 cites W2041331386 @default.
- W4311471183 cites W2041401385 @default.
- W4311471183 cites W2045556067 @default.
- W4311471183 cites W2054896953 @default.
- W4311471183 cites W2057662885 @default.
- W4311471183 cites W2057759091 @default.
- W4311471183 cites W2069666749 @default.
- W4311471183 cites W2070815002 @default.
- W4311471183 cites W2075322083 @default.
- W4311471183 cites W2078332350 @default.
- W4311471183 cites W2080452175 @default.
- W4311471183 cites W2085797297 @default.
- W4311471183 cites W2089756144 @default.
- W4311471183 cites W2094281264 @default.
- W4311471183 cites W2096420301 @default.
- W4311471183 cites W2105573994 @default.
- W4311471183 cites W2107900780 @default.
- W4311471183 cites W2129358422 @default.
- W4311471183 cites W2140063946 @default.
- W4311471183 cites W2155222181 @default.
- W4311471183 cites W2159103174 @default.
- W4311471183 cites W2166630146 @default.
- W4311471183 cites W2320041038 @default.
- W4311471183 cites W2322297706 @default.
- W4311471183 cites W2748680289 @default.
- W4311471183 cites W2758080516 @default.
- W4311471183 cites W2770162756 @default.
- W4311471183 cites W2772358396 @default.
- W4311471183 cites W2884780408 @default.
- W4311471183 cites W2888118846 @default.
- W4311471183 cites W2889653964 @default.
- W4311471183 cites W2901323278 @default.
- W4311471183 cites W2913068140 @default.
- W4311471183 cites W2952188191 @default.
- W4311471183 cites W2954450476 @default.
- W4311471183 cites W2991245955 @default.
- W4311471183 cites W2997972936 @default.
- W4311471183 cites W3012164513 @default.
- W4311471183 cites W3014351289 @default.
- W4311471183 cites W3017253802 @default.
- W4311471183 cites W3036287556 @default.
- W4311471183 cites W3037205953 @default.
- W4311471183 cites W3048808342 @default.
- W4311471183 cites W3087576394 @default.
- W4311471183 cites W3088371101 @default.
- W4311471183 cites W3094856765 @default.
- W4311471183 cites W3116823765 @default.
- W4311471183 cites W3154759673 @default.
- W4311471183 cites W3192235568 @default.
- W4311471183 cites W3199284680 @default.
- W4311471183 cites W3202051143 @default.
- W4311471183 cites W3205136792 @default.
- W4311471183 cites W3217216567 @default.
- W4311471183 cites W4225300741 @default.
- W4311471183 cites W4248684349 @default.
- W4311471183 cites W4281491751 @default.
- W4311471183 doi "https://doi.org/10.1002/admi.202202119" @default.
- W4311471183 hasPublicationYear "2022" @default.
- W4311471183 type Work @default.
- W4311471183 citedByCount "0" @default.
- W4311471183 crossrefType "journal-article" @default.
- W4311471183 hasAuthorship W4311471183A5000232732 @default.
- W4311471183 hasAuthorship W4311471183A5049260008 @default.
- W4311471183 hasAuthorship W4311471183A5055765566 @default.
- W4311471183 hasAuthorship W4311471183A5059211017 @default.
- W4311471183 hasBestOaLocation W43114711831 @default.
- W4311471183 hasConcept C108586683 @default.
- W4311471183 hasConcept C12820456 @default.
- W4311471183 hasConcept C159985019 @default.
- W4311471183 hasConcept C185592680 @default.
- W4311471183 hasConcept C188027245 @default.
- W4311471183 hasConcept C192562407 @default.
- W4311471183 hasConcept C203014093 @default.
- W4311471183 hasConcept C2777292125 @default.
- W4311471183 hasConcept C2778261982 @default.
- W4311471183 hasConcept C2779036427 @default.
- W4311471183 hasConcept C2780077467 @default.