Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311690280> ?p ?o ?g. }
- W4311690280 endingPage "15" @default.
- W4311690280 startingPage "1" @default.
- W4311690280 abstract "Annona muricata have been extensively used in traditional medicine to treat multiple diseases, including cancers. This study evaluated the genotoxic potential and antigenotoxic activities of A. muricata aqueous and ethanolic leaf extracts by employing an in vivo erythrocyte rodent micronucleus assay. Different doses (187.5, 375, and 750 mg/kg) of both extracts were administered orally for 5 days alone and combined with cyclophosphamide (CP, 60 mg/kg) to BALB/c mice. Also, it was administered orally to Wistar rats for 5 days through the final stage of gestation. No genotoxic or cytotoxic effects were observed in the two adult rodent models when A. muricata was administered orally nor in newborn rats transplacentally exposed to the extracts. Moreover, A. muricata aqueous and ethanolic leaf extracts demonstrated a protective effect against CP-induced DNA damage. Due to its lack of genotoxic effect and its capacity to decrease DNA damage, A. muricata is likely to open an interest field regarding its potential safe use in clinical applications." @default.
- W4311690280 created "2022-12-28" @default.
- W4311690280 creator A5000168435 @default.
- W4311690280 creator A5003331905 @default.
- W4311690280 creator A5046447176 @default.
- W4311690280 creator A5053704954 @default.
- W4311690280 creator A5066249799 @default.
- W4311690280 creator A5075494132 @default.
- W4311690280 creator A5082391413 @default.
- W4311690280 creator A5083694991 @default.
- W4311690280 creator A5090949199 @default.
- W4311690280 date "2022-12-16" @default.
- W4311690280 modified "2023-10-18" @default.
- W4311690280 title "Evaluation of Genotoxic Effect and Antigenotoxic Potential against DNA Damage of the Aqueous and Ethanolic Leaf Extracts of Annona muricata Using an In Vivo Erythrocyte Rodent Micronucleus Assay" @default.
- W4311690280 cites W1554121026 @default.
- W4311690280 cites W1626762175 @default.
- W4311690280 cites W1965565026 @default.
- W4311690280 cites W1971499969 @default.
- W4311690280 cites W1981366807 @default.
- W4311690280 cites W1984113624 @default.
- W4311690280 cites W1990494717 @default.
- W4311690280 cites W1999381840 @default.
- W4311690280 cites W2029525135 @default.
- W4311690280 cites W2039272476 @default.
- W4311690280 cites W2059195631 @default.
- W4311690280 cites W2074758020 @default.
- W4311690280 cites W2077820879 @default.
- W4311690280 cites W2110556045 @default.
- W4311690280 cites W2130789249 @default.
- W4311690280 cites W2130810241 @default.
- W4311690280 cites W2132172164 @default.
- W4311690280 cites W2138132897 @default.
- W4311690280 cites W2142576295 @default.
- W4311690280 cites W2149137963 @default.
- W4311690280 cites W2161309067 @default.
- W4311690280 cites W2166339036 @default.
- W4311690280 cites W2191930106 @default.
- W4311690280 cites W2283370633 @default.
- W4311690280 cites W2341280985 @default.
- W4311690280 cites W2407856755 @default.
- W4311690280 cites W2474339454 @default.
- W4311690280 cites W2512467962 @default.
- W4311690280 cites W2619071941 @default.
- W4311690280 cites W2760569565 @default.
- W4311690280 cites W2789377711 @default.
- W4311690280 cites W2794095450 @default.
- W4311690280 cites W2885160809 @default.
- W4311690280 cites W2971426989 @default.
- W4311690280 cites W2982666137 @default.
- W4311690280 cites W2985208638 @default.
- W4311690280 cites W2992157233 @default.
- W4311690280 cites W3006383944 @default.
- W4311690280 cites W3008273739 @default.
- W4311690280 cites W3107067724 @default.
- W4311690280 cites W3181541550 @default.
- W4311690280 cites W4206078381 @default.
- W4311690280 cites W4214557936 @default.
- W4311690280 doi "https://doi.org/10.1155/2022/9554011" @default.
- W4311690280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36567911" @default.
- W4311690280 hasPublicationYear "2022" @default.
- W4311690280 type Work @default.
- W4311690280 citedByCount "0" @default.
- W4311690280 crossrefType "journal-article" @default.
- W4311690280 hasAuthorship W4311690280A5000168435 @default.
- W4311690280 hasAuthorship W4311690280A5003331905 @default.
- W4311690280 hasAuthorship W4311690280A5046447176 @default.
- W4311690280 hasAuthorship W4311690280A5053704954 @default.
- W4311690280 hasAuthorship W4311690280A5066249799 @default.
- W4311690280 hasAuthorship W4311690280A5075494132 @default.
- W4311690280 hasAuthorship W4311690280A5082391413 @default.
- W4311690280 hasAuthorship W4311690280A5083694991 @default.
- W4311690280 hasAuthorship W4311690280A5090949199 @default.
- W4311690280 hasBestOaLocation W43116902801 @default.
- W4311690280 hasConcept C143425029 @default.
- W4311690280 hasConcept C150903083 @default.
- W4311690280 hasConcept C178790620 @default.
- W4311690280 hasConcept C185592680 @default.
- W4311690280 hasConcept C207001950 @default.
- W4311690280 hasConcept C2778959862 @default.
- W4311690280 hasConcept C2779565439 @default.
- W4311690280 hasConcept C29730261 @default.
- W4311690280 hasConcept C2993907526 @default.
- W4311690280 hasConcept C33070731 @default.
- W4311690280 hasConcept C36681516 @default.
- W4311690280 hasConcept C45080847 @default.
- W4311690280 hasConcept C552990157 @default.
- W4311690280 hasConcept C55493867 @default.
- W4311690280 hasConcept C556039675 @default.
- W4311690280 hasConcept C71924100 @default.
- W4311690280 hasConcept C86803240 @default.
- W4311690280 hasConcept C98274493 @default.
- W4311690280 hasConceptScore W4311690280C143425029 @default.
- W4311690280 hasConceptScore W4311690280C150903083 @default.
- W4311690280 hasConceptScore W4311690280C178790620 @default.
- W4311690280 hasConceptScore W4311690280C185592680 @default.
- W4311690280 hasConceptScore W4311690280C207001950 @default.
- W4311690280 hasConceptScore W4311690280C2778959862 @default.
- W4311690280 hasConceptScore W4311690280C2779565439 @default.