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- W4319460027 abstract "A simple and concise method for the synthesis of cinnolines has been developed by the reactions of readily available enaminones and aryl diazonium tetrafluoroboronates. The reactions run efficiently to provide cinnolines with broad diversity in the substructure by heating in dimethyl sulfoxide without using any catalyst or additive. In addition, the primary investigation of the anti-inflammatory activity of these products leads to the observation of p-chlorobenzoyl (3f) and p-nitrobenzoyl (3j) cinnolines as attractive anti-inflammatory compounds in vitro." @default.
- W4319460027 created "2023-02-09" @default.
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- W4319460027 date "2023-02-08" @default.
- W4319460027 modified "2023-10-16" @default.
- W4319460027 title "Catalyst-Free Cascade Annulation of Enaminones and Aryl Diazonium Tetrafluoroboronates for Cinnoline Synthesis and the Anti-Inflammatory Activity Study" @default.
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- W4319460027 doi "https://doi.org/10.1021/acs.joc.2c02858" @default.
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