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- W4361918079 abstract "<p>Supplementary Material and Methods: questionnaire for practical evaluation of OTL38 and the imaging system; description of immunohistochemistry and fluorescence microscopy. Fig. S1: Case report form (CRF) used to mark the location of a lesion found during surgery Fig. S2: Structure of OTL38 Fig. S3: CONSORT Flow diagram healthy volunteer study Fig. S4: Pharmacokinetics in blood plasma of healthy volunteers and patients. Fig. S5. CONSORT Flow diagram ovarian cancer patient study Fig. S6. Tumor-to-background ratio in ovarian cancer patients per dose group Fig. S7. FRα and β staining of ovarian carcinoma tissue and a metastatic lymph node Table S1. Listing of adverse events in the healthy volunteers study Table S2. Summary of pharmacokinetic parameters Table S3. Tumor-to-background ratio per dose group in ovarian cancer patients Table S4. Listing of adverse events in the patient study Table S5. Number and characteristics of lesions and lymph nodes identified with fluorescence</p>" @default.
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- W4361918079 date "2023-03-31" @default.
- W4361918079 modified "2023-10-18" @default.
- W4361918079 title "Supplementary Materials from A Novel Tumor-Specific Agent for Intraoperative Near-Infrared Fluorescence Imaging: A Translational Study in Healthy Volunteers and Patients with Ovarian Cancer" @default.
- W4361918079 doi "https://doi.org/10.1158/1078-0432.22458758.v1" @default.
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