FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4377023144> ?p ?o ?g. }

• W4377023144 abstract "Acute adrenal crisis classically presents with vomiting, altered sensorium, and hypotension. We describe a unique case manifesting with severe hypercalcemia. Addisonian crisis was unusually precipitated by fluconazole use. We reviewed other reported cases and discuss the possible mechanisms of hypercalcemia in adrenal insufficiency. This 67-year-old man presented with fever, cough, and vomiting for 1 week and with anorexia and confusion for 3 weeks. He was hypotensive and clinically dehydrated. Investigations revealed left-sided lung consolidation, acute renal failure, and severe non-parathyroid hormone (PTH)-mediated hypercalcemia (calcium, 3.55mol/L; PTH, 0.81pmol/L). Initial impression was pneumonia complicated by septic shock and hypercalcemia secondary to possible malignancy. He received mechanical ventilation; treatment with intravenous fluids, inotropes, and hydrocortisone for septic shock; and continuous renal replacement therapy with low-calcium dialysate. Although hypercalcemia resolved and he was weaned off inotropes, dialysis, and hydrocortisone, his confusion persisted. When hypercalcemia recurred on day 19 of admission, early morning cortisol was <8 nmol/L, with low ACTH level (3.2 ng/L). Other pituitary hormones were normal. Hypercalcemia resolved 3 days after reinstating stress doses of hydrocortisone, and his mentation normalized. On further questioning, he recently received fluconazole for a forearm abscess. He previously consumed traditional medications but stopped several years ago, which may have contained glucocorticoids. He was discharged on oral hydrocortisone. Cortisol levels improved gradually, and glucocorticoid replacement was ceased after 8 years, without any recurrence of hypercalcemia or Addisonian crisis. Both hypercalcemia and adrenal insufficiency may present with similar non-specific symptoms. It is important to consider adrenal insufficiency in hypercalcemia of unclear etiology." @default.
• W4377023144 created "2023-05-19" @default.
• W4377023144 creator A5006031724 @default.
• W4377023144 creator A5028579237 @default.
• W4377023144 creator A5044496772 @default.
• W4377023144 creator A5083227405 @default.
• W4377023144 date "2023-05-18" @default.
• W4377023144 modified "2023-09-26" @default.
• W4377023144 title "Case Report: Hypercalcemia as a manifestation of acute adrenal crisis precipitated by fluconazole use, and a review of the literature" @default.
• W4377023144 cites W1553491592 @default.
• W4377023144 cites W2015693375 @default.
• W4377023144 cites W2028174672 @default.
• W4377023144 cites W2033284581 @default.
• W4377023144 cites W2049374210 @default.
• W4377023144 cites W2055173008 @default.
• W4377023144 cites W2061477611 @default.
• W4377023144 cites W2066045309 @default.
• W4377023144 cites W2071793030 @default.
• W4377023144 cites W2077978841 @default.
• W4377023144 cites W2084725817 @default.
• W4377023144 cites W2085503758 @default.
• W4377023144 cites W2092562224 @default.
• W4377023144 cites W2095219104 @default.
• W4377023144 cites W2096005578 @default.
• W4377023144 cites W2119948136 @default.
• W4377023144 cites W2120898420 @default.
• W4377023144 cites W2125992435 @default.
• W4377023144 cites W2127952551 @default.
• W4377023144 cites W2133927047 @default.
• W4377023144 cites W2151830573 @default.
• W4377023144 cites W2156802549 @default.
• W4377023144 cites W2157055527 @default.
• W4377023144 cites W2410467326 @default.
• W4377023144 cites W2492513535 @default.
• W4377023144 cites W2573198204 @default.
• W4377023144 cites W2581258463 @default.
• W4377023144 cites W2784128705 @default.
• W4377023144 cites W2912512904 @default.
• W4377023144 cites W3009096972 @default.
• W4377023144 cites W3012032581 @default.
• W4377023144 cites W3035676269 @default.
• W4377023144 cites W3110544194 @default.
• W4377023144 cites W3133834469 @default.
• W4377023144 cites W3192769293 @default.
• W4377023144 cites W3203103016 @default.
• W4377023144 cites W4221009015 @default.
• W4377023144 cites W4236202223 @default.
• W4377023144 cites W2016879128 @default.
• W4377023144 doi "https://doi.org/10.3389/fendo.2023.1168797" @default.
• W4377023144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37274338" @default.
• W4377023144 hasPublicationYear "2023" @default.
• W4377023144 type Work @default.
• W4377023144 citedByCount "1" @default.
• W4377023144 countsByYear W43770231442023 @default.
• W4377023144 crossrefType "journal-article" @default.
• W4377023144 hasAuthorship W4377023144A5006031724 @default.
• W4377023144 hasAuthorship W4377023144A5028579237 @default.
• W4377023144 hasAuthorship W4377023144A5044496772 @default.
• W4377023144 hasAuthorship W4377023144A5083227405 @default.
• W4377023144 hasBestOaLocation W43770231441 @default.
• W4377023144 hasConcept C126322002 @default.
• W4377023144 hasConcept C16005928 @default.
• W4377023144 hasConcept C2777628635 @default.
• W4377023144 hasConcept C2778129406 @default.
• W4377023144 hasConcept C2778384902 @default.
• W4377023144 hasConcept C2778709874 @default.
• W4377023144 hasConcept C2778808452 @default.
• W4377023144 hasConcept C2779548794 @default.
• W4377023144 hasConcept C2780651595 @default.
• W4377023144 hasConcept C2780852908 @default.
• W4377023144 hasConcept C42219234 @default.
• W4377023144 hasConcept C71924100 @default.
• W4377023144 hasConcept C90924648 @default.
• W4377023144 hasConceptScore W4377023144C126322002 @default.
• W4377023144 hasConceptScore W4377023144C16005928 @default.
• W4377023144 hasConceptScore W4377023144C2777628635 @default.
• W4377023144 hasConceptScore W4377023144C2778129406 @default.
• W4377023144 hasConceptScore W4377023144C2778384902 @default.
• W4377023144 hasConceptScore W4377023144C2778709874 @default.
• W4377023144 hasConceptScore W4377023144C2778808452 @default.
• W4377023144 hasConceptScore W4377023144C2779548794 @default.
• W4377023144 hasConceptScore W4377023144C2780651595 @default.
• W4377023144 hasConceptScore W4377023144C2780852908 @default.
• W4377023144 hasConceptScore W4377023144C42219234 @default.
• W4377023144 hasConceptScore W4377023144C71924100 @default.
• W4377023144 hasConceptScore W4377023144C90924648 @default.
• W4377023144 hasLocation W43770231441 @default.
• W4377023144 hasLocation W43770231442 @default.
• W4377023144 hasLocation W43770231443 @default.
• W4377023144 hasOpenAccess W4377023144 @default.
• W4377023144 hasPrimaryLocation W43770231441 @default.
• W4377023144 hasRelatedWork W2042338684 @default.
• W4377023144 hasRelatedWork W2102449127 @default.
• W4377023144 hasRelatedWork W2322897425 @default.
• W4377023144 hasRelatedWork W2384704097 @default.
• W4377023144 hasRelatedWork W2748611861 @default.
• W4377023144 hasRelatedWork W2763762697 @default.
• W4377023144 hasRelatedWork W3016271834 @default.
• W4377023144 hasRelatedWork W3032687110 @default.
• W4377023144 hasRelatedWork W40371646 @default.

• next