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• W4378640329 abstract "Hepatic stellate cells (HSCs) are the key effector cells in liver fibrosis. They are the main producers of excessive amounts of extracellular matrix components during fibrogenesis and therefore a potential target for the treatment of liver fibrosis. Induction of senescence in HSCs may be a promising strategy to slow down, stop, or even reverse fibrogenesis. Senescence is a complex and heterogeneous process linked to fibrosis and cancer, but the exact mechanism and relevant markers can be cell-type dependent. Therefore, many markers of senescence have been proposed, and many methods to detect senescence have been developed. In this chapter, we review relevant methods and biomarkers to detect cellular senescence in hepatic stellate cells." @default.
• W4378640329 created "2023-05-30" @default.
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• W4378640329 date "2023-01-01" @default.
• W4378640329 modified "2023-10-16" @default.
• W4378640329 title "Studying Hepatic Stellate Cell Senescence" @default.
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• W4378640329 doi "https://doi.org/10.1007/978-1-0716-3207-9_6" @default.
• W4378640329 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37247056" @default.
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