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- W4384009958 abstract "Case presentation: A 37-year-old woman, current smoker and previously addicted to cocaine, was brought to the emergency department with complaints of “imbalance and altered speech” that started eight days prior to admission, acutely. The patient, who was previously asymptomatic, also reported fever, headache and myalgia during the same period. Emotional lability was reported by the family members. At the initial evaluation, the patient was somnolent but reactive. Scanning speech, left-sided central facial palsy, sings of bilateral pyramidal involvement, axial and appendicular cerebellar ataxia were also observed. After a thorough examination, cicatricial lesions of previous genital ulcers were observed and the patient reported the presence of recurrent orogenital ulcers in the previous three months. Also, sporadic episodes of conjunctival hyperemia and hematuria were reported. CSF analysis demonstrated a cellularity of 63 leukocytes/mm3 (100% lymphocytes), increased total protein (105 mg/dL) and a low glucose level (cerebrospinal fluid/plasma ratio of 53%). The magnetic resonance imaging showed FLAIR hyperintensity at the midbrain, left cerebral peduncle, pons (base and tegmentum), posterior limbs of both internal capsules and left posterior thalamus. A pontine lesion with peripheral contrast enhancement, leptomeningeal enhancement at the level of the prepontine cistern and enhancement of the VII and VIII complexes were also observed. High-dose steroid therapy with methylprednisolone 1 g/day was initiated (total of five days of therapy) and the patient presented significant improvement of the symptoms, returned to walk independently and no longer presented emotional lability. At the time of discharge, a mild cerebellar ataxia was still observed. The pathergy test was positive and the diagnosis of Neuro-Behçet was confirmed. The steroid treatment was transitioned to oral prednisolone and, later, immunosuppressive therapy with infliximab was started." @default.
- W4384009958 created "2023-07-13" @default.
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- W4384009958 date "2023-01-01" @default.
- W4384009958 modified "2023-09-26" @default.
- W4384009958 title "Neuro-Behçet as a cause of acute onset cerebellar ataxia: a case report" @default.
- W4384009958 doi "https://doi.org/10.5327/1516-3180.141s1.756" @default.
- W4384009958 hasPublicationYear "2023" @default.
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