Matches in SemOpenAlex for { <https://semopenalex.org/work/W4384626197> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4384626197 endingPage "6139" @default.
- W4384626197 startingPage "6132" @default.
- W4384626197 abstract "Spinal cord injury (SCI) is still one of the most challenging problems in neurosurgical practice. One of the major obstacles to neural regeneration following trauma is the formation of glial scarring and post-traumatic cysts which acts against proper growth of axons through the site of injury. Cerebrospinal fluid (CSF) delivery of bioactive agents into cystic cavities could represent a promising therapeutic strategy. In the present study, we investigated specifically the dynamics of intradural delivery of contrast medium and its relocation into post-traumatic cysts in an experimental model of spinal cord cryoinjury in rats.32 male Sprague Dawley SPF rats were submitted to injury as previously described. Omnipaque-240 was injected either into the cisterna magna or at the level of the cauda equina. Subsequently, cerebral CT scan examinations were performed in order to check the CSF dynamics of the contrast medium.There was a steady accumulation of contrast medium into post-traumatic cysts as early as five minutes after injection. A dosage of 65 mg of iodine per kilogram ensured an adequate feeling of the cysts at an average of 30 minutes.Our data indicate that intraspinal injection of bioactive agents can easily reach the site of injury and fill post-traumatic cysts. This could represent an interesting potential therapeutic protocol for SCI." @default.
- W4384626197 created "2023-07-19" @default.
- W4384626197 creator A5005991625 @default.
- W4384626197 creator A5022919608 @default.
- W4384626197 creator A5031645304 @default.
- W4384626197 creator A5046319297 @default.
- W4384626197 creator A5051484160 @default.
- W4384626197 creator A5054822453 @default.
- W4384626197 creator A5061886562 @default.
- W4384626197 creator A5077636354 @default.
- W4384626197 date "2023-07-01" @default.
- W4384626197 modified "2023-09-27" @default.
- W4384626197 title "CSF - injected contrast medium enhances post-traumatic spinal cord cysts. An experimental study in rats." @default.
- W4384626197 doi "https://doi.org/10.26355/eurrev_202307_32969" @default.
- W4384626197 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37458675" @default.
- W4384626197 hasPublicationYear "2023" @default.
- W4384626197 type Work @default.
- W4384626197 citedByCount "0" @default.
- W4384626197 crossrefType "journal-article" @default.
- W4384626197 hasAuthorship W4384626197A5005991625 @default.
- W4384626197 hasAuthorship W4384626197A5022919608 @default.
- W4384626197 hasAuthorship W4384626197A5031645304 @default.
- W4384626197 hasAuthorship W4384626197A5046319297 @default.
- W4384626197 hasAuthorship W4384626197A5051484160 @default.
- W4384626197 hasAuthorship W4384626197A5054822453 @default.
- W4384626197 hasAuthorship W4384626197A5061886562 @default.
- W4384626197 hasAuthorship W4384626197A5077636354 @default.
- W4384626197 hasConcept C102652120 @default.
- W4384626197 hasConcept C118552586 @default.
- W4384626197 hasConcept C126838900 @default.
- W4384626197 hasConcept C141071460 @default.
- W4384626197 hasConcept C142724271 @default.
- W4384626197 hasConcept C2778200158 @default.
- W4384626197 hasConcept C2778334475 @default.
- W4384626197 hasConcept C2779651940 @default.
- W4384626197 hasConcept C2779786684 @default.
- W4384626197 hasConcept C2780775167 @default.
- W4384626197 hasConcept C2781017439 @default.
- W4384626197 hasConcept C2781300204 @default.
- W4384626197 hasConcept C2994141250 @default.
- W4384626197 hasConcept C42219234 @default.
- W4384626197 hasConcept C71924100 @default.
- W4384626197 hasConceptScore W4384626197C102652120 @default.
- W4384626197 hasConceptScore W4384626197C118552586 @default.
- W4384626197 hasConceptScore W4384626197C126838900 @default.
- W4384626197 hasConceptScore W4384626197C141071460 @default.
- W4384626197 hasConceptScore W4384626197C142724271 @default.
- W4384626197 hasConceptScore W4384626197C2778200158 @default.
- W4384626197 hasConceptScore W4384626197C2778334475 @default.
- W4384626197 hasConceptScore W4384626197C2779651940 @default.
- W4384626197 hasConceptScore W4384626197C2779786684 @default.
- W4384626197 hasConceptScore W4384626197C2780775167 @default.
- W4384626197 hasConceptScore W4384626197C2781017439 @default.
- W4384626197 hasConceptScore W4384626197C2781300204 @default.
- W4384626197 hasConceptScore W4384626197C2994141250 @default.
- W4384626197 hasConceptScore W4384626197C42219234 @default.
- W4384626197 hasConceptScore W4384626197C71924100 @default.
- W4384626197 hasIssue "13" @default.
- W4384626197 hasLocation W43846261971 @default.
- W4384626197 hasOpenAccess W4384626197 @default.
- W4384626197 hasPrimaryLocation W43846261971 @default.
- W4384626197 hasRelatedWork W2003972913 @default.
- W4384626197 hasRelatedWork W2011594585 @default.
- W4384626197 hasRelatedWork W2035183491 @default.
- W4384626197 hasRelatedWork W2042372803 @default.
- W4384626197 hasRelatedWork W2053684855 @default.
- W4384626197 hasRelatedWork W2338796555 @default.
- W4384626197 hasRelatedWork W2400691453 @default.
- W4384626197 hasRelatedWork W2794158828 @default.
- W4384626197 hasRelatedWork W397538872 @default.
- W4384626197 hasRelatedWork W4384626197 @default.
- W4384626197 hasVolume "27" @default.
- W4384626197 isParatext "false" @default.
- W4384626197 isRetracted "false" @default.
- W4384626197 workType "article" @default.