FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385619611> ?p ?o ?g. }

• W4385619611 abstract "Abstract Background Periodontitis (PD) may affect temporomandibular joint disorders (TMD) and TMD may influence PD in previous observational studies. Nevertheless, these studies were prone to confounders and reverse causation, leading to incorrect conclusions about causality and direction of association. This research investigates the associations between PD and TMD employing bidirectional two-sample Mendelian randomization (MR) analysis. Methods Single-nucleotide polymorphisms (SNPs) related to PD ( p < 5 × 10 −6 ) were selected from a genome-wide association study (GWAS) from the Gene-Lifestyle Interaction in the Dental Endpoints (GLIDE) consortium, and related these to SNPs from FinnGen and UK Biobank (UKB) consortia, and vice versa. We implemented the standard inverse variance weighted (IVW), weighted median (WM), MR-Egger regression, and MR-PRESSO methods to estimate the potential causality between PD and TMD. Sensitive tests were conducted using robust MR methods. Results from FinnGen and UKB were combined using the fixed model. Results PD did not appear to causally affect TMD. Additionally, the reverse MR analysis did not reveal a significant causal effect of TMD on PD. The results of other MR methods were similar to those of the IVW method. Sensitivity analyses addressed no potential pleiotropy in MR estimations. Results from the meta-analysis were consistent with the above-mentioned consequences. Conclusion This research does not support a causal relationship between PD and TMD. PD does not appear to worsen TMD directly, and vice versa." @default.
• W4385619611 created "2023-08-08" @default.
• W4385619611 creator A5003137188 @default.
• W4385619611 creator A5030729920 @default.
• W4385619611 creator A5054742084 @default.
• W4385619611 creator A5073143493 @default.
• W4385619611 creator A5086099403 @default.
• W4385619611 creator A5091878912 @default.
• W4385619611 date "2023-08-08" @default.
• W4385619611 modified "2023-10-14" @default.
• W4385619611 title "Association between periodontitis and temporomandibular joint disorders" @default.
• W4385619611 cites W1884908088 @default.
• W4385619611 cites W1905058580 @default.
• W4385619611 cites W2088917407 @default.
• W4385619611 cites W2113699335 @default.
• W4385619611 cites W2117889691 @default.
• W4385619611 cites W2129280823 @default.
• W4385619611 cites W2324862792 @default.
• W4385619611 cites W2467367039 @default.
• W4385619611 cites W2536687083 @default.
• W4385619611 cites W2577841140 @default.
• W4385619611 cites W2610723828 @default.
• W4385619611 cites W2728017684 @default.
• W4385619611 cites W2769644907 @default.
• W4385619611 cites W2803072880 @default.
• W4385619611 cites W2803276548 @default.
• W4385619611 cites W2906185906 @default.
• W4385619611 cites W2945665018 @default.
• W4385619611 cites W2946948176 @default.
• W4385619611 cites W3028524479 @default.
• W4385619611 cites W3047193582 @default.
• W4385619611 cites W3081351409 @default.
• W4385619611 cites W3097866686 @default.
• W4385619611 cites W3110567601 @default.
• W4385619611 cites W3125030132 @default.
• W4385619611 cites W3134991047 @default.
• W4385619611 cites W3138341968 @default.
• W4385619611 cites W3194127268 @default.
• W4385619611 cites W3203751815 @default.
• W4385619611 cites W3210382439 @default.
• W4385619611 cites W4220935206 @default.
• W4385619611 cites W4224980560 @default.
• W4385619611 cites W4242494189 @default.
• W4385619611 cites W4317390883 @default.
• W4385619611 doi "https://doi.org/10.1186/s13075-023-03129-0" @default.
• W4385619611 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37550788" @default.
• W4385619611 hasPublicationYear "2023" @default.
• W4385619611 type Work @default.
• W4385619611 citedByCount "0" @default.
• W4385619611 crossrefType "journal-article" @default.
• W4385619611 hasAuthorship W4385619611A5003137188 @default.
• W4385619611 hasAuthorship W4385619611A5030729920 @default.
• W4385619611 hasAuthorship W4385619611A5054742084 @default.
• W4385619611 hasAuthorship W4385619611A5073143493 @default.
• W4385619611 hasAuthorship W4385619611A5086099403 @default.
• W4385619611 hasAuthorship W4385619611A5091878912 @default.
• W4385619611 hasBestOaLocation W43856196111 @default.
• W4385619611 hasConcept C104317684 @default.
• W4385619611 hasConcept C106208931 @default.
• W4385619611 hasConcept C121332964 @default.
• W4385619611 hasConcept C126322002 @default.
• W4385619611 hasConcept C127716648 @default.
• W4385619611 hasConcept C135763542 @default.
• W4385619611 hasConcept C153209595 @default.
• W4385619611 hasConcept C186413461 @default.
• W4385619611 hasConcept C23131810 @default.
• W4385619611 hasConcept C26207810 @default.
• W4385619611 hasConcept C2779901538 @default.
• W4385619611 hasConcept C2780385504 @default.
• W4385619611 hasConcept C2993967602 @default.
• W4385619611 hasConcept C54355233 @default.
• W4385619611 hasConcept C60644358 @default.
• W4385619611 hasConcept C62520636 @default.
• W4385619611 hasConcept C64357122 @default.
• W4385619611 hasConcept C71924100 @default.
• W4385619611 hasConcept C77350462 @default.
• W4385619611 hasConcept C86803240 @default.
• W4385619611 hasConceptScore W4385619611C104317684 @default.
• W4385619611 hasConceptScore W4385619611C106208931 @default.
• W4385619611 hasConceptScore W4385619611C121332964 @default.
• W4385619611 hasConceptScore W4385619611C126322002 @default.
• W4385619611 hasConceptScore W4385619611C127716648 @default.
• W4385619611 hasConceptScore W4385619611C135763542 @default.
• W4385619611 hasConceptScore W4385619611C153209595 @default.
• W4385619611 hasConceptScore W4385619611C186413461 @default.
• W4385619611 hasConceptScore W4385619611C23131810 @default.
• W4385619611 hasConceptScore W4385619611C26207810 @default.
• W4385619611 hasConceptScore W4385619611C2779901538 @default.
• W4385619611 hasConceptScore W4385619611C2780385504 @default.
• W4385619611 hasConceptScore W4385619611C2993967602 @default.
• W4385619611 hasConceptScore W4385619611C54355233 @default.
• W4385619611 hasConceptScore W4385619611C60644358 @default.
• W4385619611 hasConceptScore W4385619611C62520636 @default.
• W4385619611 hasConceptScore W4385619611C64357122 @default.
• W4385619611 hasConceptScore W4385619611C71924100 @default.
• W4385619611 hasConceptScore W4385619611C77350462 @default.
• W4385619611 hasConceptScore W4385619611C86803240 @default.
• W4385619611 hasFunder F4320321001 @default.
• W4385619611 hasIssue "1" @default.
• W4385619611 hasLocation W43856196111 @default.

• next