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• W4385754268 abstract "In their application in medical devices, zirconium (Zr) and its alloys are expected to prevent the generation of magnetic resonance imaging artifacts owing to their magnetic susceptibilities. The one-step micro-arc oxidation (MAO) process in electrolytes of phosphate, calcium, and silver (Ag) ions may endow the Zr surface with osteogenic cell compatibility and antibacterial activity, owing to the formation of porous oxide layers consisting of the electrolyte and substrate elements. Herein, we formed Ag-incorporated porous oxide layers on Zr and titanium (Ti) surfaces with MAO, and their surface structure, composition, chemical state, and biofunctions were investigated. The results showed that the surface structure and composition of the resulting oxide layers were affected by the metallic substrate. The chemical states of Ag in the resulting oxide layer differed between the Ti and Zr substrates. Moreover, the amount of Ag ions released from the Zr surface was lower than that released from the Ti surface, despite the surface Ag concentration of Zr being higher than that of Ti. After 24 h of incubation, the viability of MC3T3-E1 cells and Staphylococcus aureus on the Ag-incorporated oxide layers on the Zr substrate was significantly higher than that on the Ti substrate. Therefore, the Ag-incorporated oxide layer was more chemically stable on the Zr substrate. Specifically, the different Ag chemical states in the oxide layer caused by the metallic substrate affected the osteogenic cell compatibility and antibacterial activity of the resulting oxide layers formed by MAO. Our findings provide fundamental insights into the surface design of Zr-based medical devices to prevent magnetic resonance imaging artifacts." @default.
• W4385754268 created "2023-08-12" @default.
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• W4385754268 date "2023-08-11" @default.
• W4385754268 modified "2023-10-11" @default.
• W4385754268 title "Metallic Substrate Influences on the Osteogenic Cell Compatibility and Antibacterial Activity of Silver-Incorporated Porous Oxide Layers Formed by Micro-Arc Oxidation" @default.
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• W4385754268 doi "https://doi.org/10.1021/acsaenm.3c00332" @default.
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