FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387343343> ?p ?o ?g. }

• W4387343343 abstract "Objective To investigate the impact of optimized thrombus aspiration on myocardial perfusion, prognosis, and safety in patients with acute ST - segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention(primary PCI). Methods A total of 129 patients with STEMI were randomly allocated into control group (Subgroup A and B) and experimental group(Subgroup C and D). Control group received percutaneous transluminal coronary angioplasty (PTCA),thrombus aspiration and primary PCI. Experimental group received optimized thrombus aspiration and primary PCI. The number of thrombus aspiration was less than 4 times in Subgroup A and C. The number of thrombus aspiration was performed more than 4 times in Subgroups B and D. The classification of thrombi extracted, the TIMI flow grade, the incidence of no-reflow and slow flow, cTFC, TPI and CK-MB at 12 h and 24 h after stenting, ST segment resolution of ECG after stenting, NT-proBNP, LVEFat 24 h, 30 days and 180 days after stenting were compared between groups. The incidence of intraoperative and postoperative bleeding complications, stroke events and major cardiovascular events (MACE) were recorded and compared between groups. Results The classification of thrombi extracted in the experimental group was higher than that in the control group. The TIMI flow grade of the experimental group was better than the control group after thrombus aspiration. After stenting, the advantage still existed, but the difference was not statistically significant. On cTFC, the experimental group was lower than the control group, but the difference was not statistically significant; After stenting the experimental group was significantly lower than the control group. The CK-MB at 12 h and 24 h of the experimental group was lower than the control group. After thrombus aspiration the incidence of no-reflow in the experimental group was significantly lower than that in the control group; after stenting the incidence of no-reflow in the experimental group was still lower than the control group, but no statistically difference. After thrombus aspiration and stenting the incidence of slow flow in the experimental group were lower than that in the control group. After stenting, NT-proBNP at 24 h was lower in the experimental group than that in the control group, However, there was no statistical difference; after stenting, The NT-proBNP in the experimental group was lower than that in the control group at 30 days and 180 days. After stenting, LVEF of the experimental group was significantly higher than the control group at 24 h and 30 days; superiority remained after 180 days but no statistical difference. There was no statistical difference between two groups for intraoperative and postoperative bleeding complications, stroke events, and MACE events. In Subgroup analysis,there was no significant difference in the classification of thrombi extracted, TIMI flow grade, cTFC, CK-MB,NT-proBNP and LVEF between group C and D, but group A was better than group B. Analysis of variance showed that the optimal number of suction was 4–5 times. Conclusions Optimized thrombus aspiration can significantly improve myocardial perfusion and short-term and medium-term prognosis of STEMI patients after PCI, and reduce the incidence of slow flow and no-reflow. The optimal suction times were 4–5 times. Traditional aspiration method with more aspiration times is harmful to cardiac prognosis. Thrombus aspiration does not increase the incidence of stroke events and is safe. Clinical Trial Registration : identifier, ChiCTR2300073410." @default.
• W4387343343 created "2023-10-05" @default.
• W4387343343 creator A5003799076 @default.
• W4387343343 creator A5006397303 @default.
• W4387343343 creator A5007329497 @default.
• W4387343343 creator A5009485286 @default.
• W4387343343 creator A5021746201 @default.
• W4387343343 creator A5034579880 @default.
• W4387343343 creator A5040267498 @default.
• W4387343343 creator A5053969245 @default.
• W4387343343 creator A5069542602 @default.
• W4387343343 creator A5072357964 @default.
• W4387343343 creator A5075782732 @default.
• W4387343343 creator A5086830713 @default.
• W4387343343 date "2023-10-04" @default.
• W4387343343 modified "2023-10-06" @default.
• W4387343343 title "Effect of optimized thrombus aspiration on myocardial perfusion and prognosis in acute ST-segment elevation myocardial infarction patients with primary percutaneous coronary intervention" @default.
• W4387343343 cites W1612386430 @default.
• W4387343343 cites W1765482651 @default.
• W4387343343 cites W1951099349 @default.
• W4387343343 cites W1982667819 @default.
• W4387343343 cites W2006556934 @default.
• W4387343343 cites W2078105529 @default.
• W4387343343 cites W2113350818 @default.
• W4387343343 cites W2120927357 @default.
• W4387343343 cites W2121908294 @default.
• W4387343343 cites W2171031458 @default.
• W4387343343 cites W2505996607 @default.
• W4387343343 cites W2586965858 @default.
• W4387343343 cites W2754054868 @default.
• W4387343343 cites W2968139477 @default.
• W4387343343 cites W2988480211 @default.
• W4387343343 cites W3008364813 @default.
• W4387343343 cites W4236531408 @default.
• W4387343343 doi "https://doi.org/10.3389/fcvm.2023.1249924" @default.
• W4387343343 hasPublicationYear "2023" @default.
• W4387343343 type Work @default.
• W4387343343 citedByCount "0" @default.
• W4387343343 crossrefType "journal-article" @default.
• W4387343343 hasAuthorship W4387343343A5003799076 @default.
• W4387343343 hasAuthorship W4387343343A5006397303 @default.
• W4387343343 hasAuthorship W4387343343A5007329497 @default.
• W4387343343 hasAuthorship W4387343343A5009485286 @default.
• W4387343343 hasAuthorship W4387343343A5021746201 @default.
• W4387343343 hasAuthorship W4387343343A5034579880 @default.
• W4387343343 hasAuthorship W4387343343A5040267498 @default.
• W4387343343 hasAuthorship W4387343343A5053969245 @default.
• W4387343343 hasAuthorship W4387343343A5069542602 @default.
• W4387343343 hasAuthorship W4387343343A5072357964 @default.
• W4387343343 hasAuthorship W4387343343A5075782732 @default.
• W4387343343 hasAuthorship W4387343343A5086830713 @default.
• W4387343343 hasBestOaLocation W43873433431 @default.
• W4387343343 hasConcept C126322002 @default.
• W4387343343 hasConcept C146957229 @default.
• W4387343343 hasConcept C164705383 @default.
• W4387343343 hasConcept C2771771 @default.
• W4387343343 hasConcept C2777995511 @default.
• W4387343343 hasConcept C2779581417 @default.
• W4387343343 hasConcept C2780326628 @default.
• W4387343343 hasConcept C2780400711 @default.
• W4387343343 hasConcept C2780739214 @default.
• W4387343343 hasConcept C2781362458 @default.
• W4387343343 hasConcept C45393284 @default.
• W4387343343 hasConcept C500558357 @default.
• W4387343343 hasConcept C71924100 @default.
• W4387343343 hasConceptScore W4387343343C126322002 @default.
• W4387343343 hasConceptScore W4387343343C146957229 @default.
• W4387343343 hasConceptScore W4387343343C164705383 @default.
• W4387343343 hasConceptScore W4387343343C2771771 @default.
• W4387343343 hasConceptScore W4387343343C2777995511 @default.
• W4387343343 hasConceptScore W4387343343C2779581417 @default.
• W4387343343 hasConceptScore W4387343343C2780326628 @default.
• W4387343343 hasConceptScore W4387343343C2780400711 @default.
• W4387343343 hasConceptScore W4387343343C2780739214 @default.
• W4387343343 hasConceptScore W4387343343C2781362458 @default.
• W4387343343 hasConceptScore W4387343343C45393284 @default.
• W4387343343 hasConceptScore W4387343343C500558357 @default.
• W4387343343 hasConceptScore W4387343343C71924100 @default.
• W4387343343 hasLocation W43873433431 @default.
• W4387343343 hasOpenAccess W4387343343 @default.
• W4387343343 hasPrimaryLocation W43873433431 @default.
• W4387343343 hasRelatedWork W2086524969 @default.
• W4387343343 hasRelatedWork W2127687375 @default.
• W4387343343 hasRelatedWork W2313109464 @default.
• W4387343343 hasRelatedWork W2361737867 @default.
• W4387343343 hasRelatedWork W2363980427 @default.
• W4387343343 hasRelatedWork W2374929624 @default.
• W4387343343 hasRelatedWork W2386737985 @default.
• W4387343343 hasRelatedWork W2394748619 @default.
• W4387343343 hasRelatedWork W2803744020 @default.
• W4387343343 hasRelatedWork W3029448752 @default.
• W4387343343 hasVolume "10" @default.
• W4387343343 isParatext "false" @default.
• W4387343343 isRetracted "false" @default.
• W4387343343 workType "article" @default.