Matches in SemOpenAlex for { <https://semopenalex.org/work/W4387439420> ?p ?o ?g. }
- W4387439420 abstract "This study investigates the functional brain connectivity in patients with anterior knee pain (AKP). While biomechanical models are frequently employed to investigate AKP, it is important to recognize that pain can manifest even in the absence of structural abnormalities. Leveraging the capabilities of functional magnetic resonance imaging (fMRI), this research aims to investigate the brain mechanisms present in AKP patients.Forty-five female subjects (24 AKP patients, 21 controls) underwent resting-state fMRI and T1-weighted structural MRI. Functional brain connectivity patterns were analyzed, focusing on pain network areas, and the influence of catastrophizing thoughts was evaluated.Comparing patients and controls, several findings emerged. First, patients with AKP exhibited increased correlation between the right supplementary motor area and cerebellum I, as well as decreased correlation between the right insula and the left rostral prefrontal cortex and superior frontal gyrus. Second, in AKP patients with catastrophizing thoughts, there was increased correlation of the left lateral parietal cortex with two regions of the right cerebellum (II and VII) and the right pallidum, and decreased correlation between the left medial frontal gyrus and the right thalamus. Furthermore, the correlation between these regions showed promising results for discriminating AKP patients from controls, achieving a cross-validation accuracy of 80.5%.Resting-state fMRI revealed correlation differences in AKP patients compared to controls and based on catastrophizing thoughts levels. These findings shed light on neural correlates of chronic pain in AKP, suggesting that functional brain connectivity alterations may be linked to pain experience in this population.Etiopathogenesis of pain in anterior knee pain patients might not be limited to the knee, but also to underlying alterations in the central nervous system: cortical changes might lead a perpetuation of pain.• Anterior knee pain patients exhibit distinct functional brain connectivity compared to controls, and among catastrophizing subgroups. • Resting-state fMRI reveals potential for discriminating anterior knee pain patients with 80.5% accuracy. • Functional brain connectivity differences improve understanding of pain pathogenesis and objective anterior knee pain identification." @default.
- W4387439420 created "2023-10-10" @default.
- W4387439420 creator A5006992022 @default.
- W4387439420 creator A5019557710 @default.
- W4387439420 creator A5020818219 @default.
- W4387439420 creator A5028700235 @default.
- W4387439420 creator A5031877710 @default.
- W4387439420 creator A5034986814 @default.
- W4387439420 creator A5043511309 @default.
- W4387439420 creator A5072387429 @default.
- W4387439420 date "2023-10-09" @default.
- W4387439420 modified "2023-10-18" @default.
- W4387439420 title "Brain network functional connectivity changes in patients with anterior knee pain: a resting-state fMRI exploratory study" @default.
- W4387439420 cites W1544030801 @default.
- W4387439420 cites W1845447069 @default.
- W4387439420 cites W1937888893 @default.
- W4387439420 cites W1969764722 @default.
- W4387439420 cites W1983183519 @default.
- W4387439420 cites W2000338428 @default.
- W4387439420 cites W2009750474 @default.
- W4387439420 cites W2016293149 @default.
- W4387439420 cites W2022069844 @default.
- W4387439420 cites W2030899577 @default.
- W4387439420 cites W2055345898 @default.
- W4387439420 cites W2058767401 @default.
- W4387439420 cites W2072357085 @default.
- W4387439420 cites W2091919804 @default.
- W4387439420 cites W2107754415 @default.
- W4387439420 cites W2109173536 @default.
- W4387439420 cites W2110065044 @default.
- W4387439420 cites W2113217511 @default.
- W4387439420 cites W2130010412 @default.
- W4387439420 cites W2147546041 @default.
- W4387439420 cites W2156514802 @default.
- W4387439420 cites W2160662805 @default.
- W4387439420 cites W2166281097 @default.
- W4387439420 cites W2168529864 @default.
- W4387439420 cites W2324129055 @default.
- W4387439420 cites W246600485 @default.
- W4387439420 cites W2470779975 @default.
- W4387439420 cites W2560455636 @default.
- W4387439420 cites W2598180297 @default.
- W4387439420 cites W2767516494 @default.
- W4387439420 cites W2782813784 @default.
- W4387439420 cites W2898371092 @default.
- W4387439420 cites W2912440774 @default.
- W4387439420 cites W2919931959 @default.
- W4387439420 cites W2937369405 @default.
- W4387439420 cites W3109089544 @default.
- W4387439420 cites W3189785145 @default.
- W4387439420 cites W4327850204 @default.
- W4387439420 doi "https://doi.org/10.1186/s41747-023-00378-1" @default.
- W4387439420 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37806998" @default.
- W4387439420 hasPublicationYear "2023" @default.
- W4387439420 type Work @default.
- W4387439420 citedByCount "0" @default.
- W4387439420 crossrefType "journal-article" @default.
- W4387439420 hasAuthorship W4387439420A5006992022 @default.
- W4387439420 hasAuthorship W4387439420A5019557710 @default.
- W4387439420 hasAuthorship W4387439420A5020818219 @default.
- W4387439420 hasAuthorship W4387439420A5028700235 @default.
- W4387439420 hasAuthorship W4387439420A5031877710 @default.
- W4387439420 hasAuthorship W4387439420A5034986814 @default.
- W4387439420 hasAuthorship W4387439420A5043511309 @default.
- W4387439420 hasAuthorship W4387439420A5072387429 @default.
- W4387439420 hasBestOaLocation W43874394201 @default.
- W4387439420 hasConcept C104996578 @default.
- W4387439420 hasConcept C117220453 @default.
- W4387439420 hasConcept C15744967 @default.
- W4387439420 hasConcept C169760540 @default.
- W4387439420 hasConcept C2524010 @default.
- W4387439420 hasConcept C2775956885 @default.
- W4387439420 hasConcept C2779226451 @default.
- W4387439420 hasConcept C2779369059 @default.
- W4387439420 hasConcept C2781300654 @default.
- W4387439420 hasConcept C2781449700 @default.
- W4387439420 hasConcept C33923547 @default.
- W4387439420 hasConcept C548259974 @default.
- W4387439420 hasConcept C66324658 @default.
- W4387439420 hasConcept C71924100 @default.
- W4387439420 hasConceptScore W4387439420C104996578 @default.
- W4387439420 hasConceptScore W4387439420C117220453 @default.
- W4387439420 hasConceptScore W4387439420C15744967 @default.
- W4387439420 hasConceptScore W4387439420C169760540 @default.
- W4387439420 hasConceptScore W4387439420C2524010 @default.
- W4387439420 hasConceptScore W4387439420C2775956885 @default.
- W4387439420 hasConceptScore W4387439420C2779226451 @default.
- W4387439420 hasConceptScore W4387439420C2779369059 @default.
- W4387439420 hasConceptScore W4387439420C2781300654 @default.
- W4387439420 hasConceptScore W4387439420C2781449700 @default.
- W4387439420 hasConceptScore W4387439420C33923547 @default.
- W4387439420 hasConceptScore W4387439420C548259974 @default.
- W4387439420 hasConceptScore W4387439420C66324658 @default.
- W4387439420 hasConceptScore W4387439420C71924100 @default.
- W4387439420 hasIssue "1" @default.
- W4387439420 hasLocation W43874394201 @default.
- W4387439420 hasLocation W43874394202 @default.
- W4387439420 hasOpenAccess W4387439420 @default.
- W4387439420 hasPrimaryLocation W43874394201 @default.
- W4387439420 hasRelatedWork W1985126645 @default.