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• W4387608450 abstract "By intercalating montmorillonite (MMT) with Cu2+ and benzalkonium chloride (BAC), the present work constructed a synergistic promotion system (Cu2+/BAC/MMT). MMT not only enhances the thermal stability of Cu2+ and BAC but also facilitates the controlled release of Cu2+ and BAC. Concurrently, the introduction of BAC improves the material's organic compatibility. In vitro assays show that the MIC+ of Cu2+/BAC/MMT against Staphylococcus aureus is merely 7.32 mg/L and 55.56 mg/L against Escherichia coli. At concentrations of 10 and 25 mg/L, Cu2+/BAC/MMT inactivates 100% of S. aureus and E. coli within 2 h, respectively. Furthermore, it is confirmed that the prepared Cu2+/BAC/MMT exhibits a long-term antibacterial ability through antibacterial experiments and release tests. Also, the biosafety of this material was also substantiated by in vitro cytotoxicity tests. These comprehensive findings indisputably portend that Cu2+/BAC/MMT holds promise to supplant antibiotics as an efficacious treatment modality for bacterial infections." @default.
• W4387608450 created "2023-10-14" @default.
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• W4387608450 date "2023-10-13" @default.
• W4387608450 modified "2023-10-15" @default.
• W4387608450 title "Synergistic Promotion System of Montmorillonite with Cu²⁺ and Benzalkonium Chloride for Efficient and Broad-Spectrum Antibacterial Activity" @default.
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• W4387608450 doi "https://doi.org/10.1021/acsabm.3c00655" @default.
• W4387608450 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37832028" @default.
• W4387608450 hasPublicationYear "2023" @default.
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