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- W45024961 abstract "Soft tissue sarcomas represent a diverse collection of mesenchymal tumors which affect both children and adults. A variety of different mutations and cell types play a role in sarcoma formation, and this has complicated efforts to discover its cell of origin. In this chapter, we will first provide a general background of the sarcoma field including common mutations and involved cell types. We will then focus on rhabdomyosarcoma and reveal how knowledge from normal stem cell biology and differentiation has provided tools to enable powerful studies in genetically engineered mice." @default.
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- W45024961 date "2012-01-01" @default.
- W45024961 modified "2023-09-25" @default.
- W45024961 title "Initiation of Soft Tissue Sarcomas: Muscle Stem/Progenitor Cells as Targets" @default.
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- W45024961 doi "https://doi.org/10.1007/978-94-007-4285-7_12" @default.
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