Matches in SemOpenAlex for { <https://semopenalex.org/work/W5572009> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W5572009 endingPage "8" @default.
- W5572009 startingPage "323" @default.
- W5572009 abstract "The effect of kinnow juice on the pharmacokinetics of a single dose of sustained release theophylline was investigated in healthy male volunteers. In a two phased open cross-over randomized study, ten healthy male volunteers were given sustained release theophylline (300 mg) along with 300 ml of water or kinnow juice, a routinely used citrus juice in India. Blood samples were collected at different time points from 0-48 hours. Plasma was assayed for theophylline by a HPLC method and various pharmacokinetic parameters were calculated and compared. The theophylline levels were lower at all the time points with kinnow juice co-administration as compared to water but were significantly so only during the absorption phase from 1-4 hours. The values for all the pharmacokinetic parameters evaluated were on the lower side with kinnow juice except Tmax which was slightly delayed. None of these alterations was found to be significantly different. The results indicate that since there is an interference with the absorption of the drug, the patients may be advised not to consume kinnow juice when taking a slow release theophylline preparation and the monitoring of plasma concentrations of theophylline in patients who routinely consume kinnow juice in their diet might be helpful in better management of these patients." @default.
- W5572009 created "2016-06-24" @default.
- W5572009 creator A5025156542 @default.
- W5572009 creator A5028519544 @default.
- W5572009 creator A5034253070 @default.
- W5572009 date "2000-07-01" @default.
- W5572009 modified "2023-09-25" @default.
- W5572009 title "Influence of kinnow juice on the pharmacokinetics of sustained release theophylline in healthy male volunteers." @default.
- W5572009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10941621" @default.
- W5572009 hasPublicationYear "2000" @default.
- W5572009 type Work @default.
- W5572009 sameAs 5572009 @default.
- W5572009 citedByCount "0" @default.
- W5572009 crossrefType "journal-article" @default.
- W5572009 hasAuthorship W5572009A5025156542 @default.
- W5572009 hasAuthorship W5572009A5028519544 @default.
- W5572009 hasAuthorship W5572009A5034253070 @default.
- W5572009 hasConcept C112705442 @default.
- W5572009 hasConcept C121332964 @default.
- W5572009 hasConcept C125287762 @default.
- W5572009 hasConcept C126322002 @default.
- W5572009 hasConcept C185592680 @default.
- W5572009 hasConcept C24890656 @default.
- W5572009 hasConcept C2776042228 @default.
- W5572009 hasConcept C2776773239 @default.
- W5572009 hasConcept C2778095195 @default.
- W5572009 hasConcept C2781018748 @default.
- W5572009 hasConcept C3018968983 @default.
- W5572009 hasConcept C31903555 @default.
- W5572009 hasConcept C71924100 @default.
- W5572009 hasConcept C98274493 @default.
- W5572009 hasConceptScore W5572009C112705442 @default.
- W5572009 hasConceptScore W5572009C121332964 @default.
- W5572009 hasConceptScore W5572009C125287762 @default.
- W5572009 hasConceptScore W5572009C126322002 @default.
- W5572009 hasConceptScore W5572009C185592680 @default.
- W5572009 hasConceptScore W5572009C24890656 @default.
- W5572009 hasConceptScore W5572009C2776042228 @default.
- W5572009 hasConceptScore W5572009C2776773239 @default.
- W5572009 hasConceptScore W5572009C2778095195 @default.
- W5572009 hasConceptScore W5572009C2781018748 @default.
- W5572009 hasConceptScore W5572009C3018968983 @default.
- W5572009 hasConceptScore W5572009C31903555 @default.
- W5572009 hasConceptScore W5572009C71924100 @default.
- W5572009 hasConceptScore W5572009C98274493 @default.
- W5572009 hasIssue "3" @default.
- W5572009 hasLocation W55720091 @default.
- W5572009 hasOpenAccess W5572009 @default.
- W5572009 hasPrimaryLocation W55720091 @default.
- W5572009 hasRelatedWork W1976328537 @default.
- W5572009 hasRelatedWork W2004032404 @default.
- W5572009 hasRelatedWork W2034663435 @default.
- W5572009 hasRelatedWork W2068285358 @default.
- W5572009 hasRelatedWork W2084365251 @default.
- W5572009 hasRelatedWork W2164754849 @default.
- W5572009 hasRelatedWork W2325795327 @default.
- W5572009 hasRelatedWork W2426732143 @default.
- W5572009 hasRelatedWork W2974245363 @default.
- W5572009 hasRelatedWork W5572009 @default.
- W5572009 hasVolume "44" @default.
- W5572009 isParatext "false" @default.
- W5572009 isRetracted "false" @default.
- W5572009 magId "5572009" @default.
- W5572009 workType "article" @default.