FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W62067653> ?p ?o ?g. }

• W62067653 abstract "The increased risk of cardiovascular disease (CVD) amongst South Asians (SAs) is unclear. This thesis examined potential biomarkers to address this. Cross-sectional data on SAs from community (n=1304) and hospital (n=148) populations was collected. Biomarkers were analysed by genotyping, mass spectrometry, automated-immuno-colourimetric-assays, ELISAs, and a new in-house assay for a novel marker, ferritin bound to apolipoprotein B. Diagnostic performance was assessed using receiver operating curves, logistic and linear regression models. C-reactive protein (CRP) was a comprehensive marker of CVD risk, where a range of 1.43-2.30 mg/L maximised sensitivity and specificity. CRP SNP (single nucleotide polymorphism) -390C>T/A contributed minimally to variation in CRP levels. Non-fasting triglycerides discriminated SAs at increased CVD risk, where APOA5 SNP -1131T>C was an independent predictor of triglycerides but APOC3 SNP -455T>C and -482C>T were not associated with triglycerides. The performance of IL-6, vWF, D-dimer and P-selectin were poor in comparison to CRP and triglycerides. BNP discriminated SAs with systolic heart failure with a cut off value of 36.4 pmol/l. Of the newly investigated biomarkers, a link between haemoglobin abnormalities and CVD was observed potentially through a mechanism involving iron transportation on lipoproteins. CRP and triglycerides should be considered in the routine CVD risk assessment of SAs." @default.
• W62067653 created "2016-06-24" @default.
• W62067653 creator A5083723350 @default.
• W62067653 date "2013-12-01" @default.
• W62067653 modified "2023-09-27" @default.
• W62067653 title "Antecedents, characterisation and validity of cardiovascular disease biomarkers amongst South Asians in the UK" @default.
• W62067653 cites W1232499 @default.
• W62067653 cites W14674810 @default.
• W62067653 cites W1480665734 @default.
• W62067653 cites W1501968584 @default.
• W62067653 cites W1514079210 @default.
• W62067653 cites W1540456652 @default.
• W62067653 cites W1570002688 @default.
• W62067653 cites W1596038729 @default.
• W62067653 cites W180144476 @default.
• W62067653 cites W1826153332 @default.
• W62067653 cites W1932708174 @default.
• W62067653 cites W1934442814 @default.
• W62067653 cites W1950462993 @default.
• W62067653 cites W1950591873 @default.
• W62067653 cites W1952122488 @default.
• W62067653 cites W1963872182 @default.
• W62067653 cites W1964779770 @default.
• W62067653 cites W1964873102 @default.
• W62067653 cites W1967252933 @default.
• W62067653 cites W1967437309 @default.
• W62067653 cites W1967958015 @default.
• W62067653 cites W1969776575 @default.
• W62067653 cites W1969927159 @default.
• W62067653 cites W1971114246 @default.
• W62067653 cites W1971903720 @default.
• W62067653 cites W1972919038 @default.
• W62067653 cites W1975161958 @default.
• W62067653 cites W1976057876 @default.
• W62067653 cites W1976248362 @default.
• W62067653 cites W1976428272 @default.
• W62067653 cites W1979003242 @default.
• W62067653 cites W1980459953 @default.
• W62067653 cites W1981237781 @default.
• W62067653 cites W1981276886 @default.
• W62067653 cites W1982703745 @default.
• W62067653 cites W1982741524 @default.
• W62067653 cites W1983983801 @default.
• W62067653 cites W1984662191 @default.
• W62067653 cites W1984797067 @default.
• W62067653 cites W1985761406 @default.
• W62067653 cites W1985967126 @default.
• W62067653 cites W1986122868 @default.
• W62067653 cites W1987208426 @default.
• W62067653 cites W1988210709 @default.
• W62067653 cites W1988366654 @default.
• W62067653 cites W1988495648 @default.
• W62067653 cites W1988816170 @default.
• W62067653 cites W1989249306 @default.
• W62067653 cites W1989258056 @default.
• W62067653 cites W1989323378 @default.
• W62067653 cites W1991037578 @default.
• W62067653 cites W1991462308 @default.
• W62067653 cites W1991685221 @default.
• W62067653 cites W1992435064 @default.
• W62067653 cites W1992486326 @default.
• W62067653 cites W1995012519 @default.
• W62067653 cites W1996961471 @default.
• W62067653 cites W1998350487 @default.
• W62067653 cites W1999508217 @default.
• W62067653 cites W1999723567 @default.
• W62067653 cites W2001979704 @default.
• W62067653 cites W2001980982 @default.
• W62067653 cites W2004492804 @default.
• W62067653 cites W2005624575 @default.
• W62067653 cites W2007933314 @default.
• W62067653 cites W2007946529 @default.
• W62067653 cites W2008014499 @default.
• W62067653 cites W2009113903 @default.
• W62067653 cites W2011402537 @default.
• W62067653 cites W2014663082 @default.
• W62067653 cites W2015511799 @default.
• W62067653 cites W2015693493 @default.
• W62067653 cites W2016222283 @default.
• W62067653 cites W2016827868 @default.
• W62067653 cites W2016918979 @default.
• W62067653 cites W2018058963 @default.
• W62067653 cites W2018135697 @default.
• W62067653 cites W2018237542 @default.
• W62067653 cites W2018271117 @default.
• W62067653 cites W2019358153 @default.
• W62067653 cites W2019779002 @default.
• W62067653 cites W2020030307 @default.
• W62067653 cites W2021029105 @default.
• W62067653 cites W2022438446 @default.
• W62067653 cites W2022996249 @default.
• W62067653 cites W2023466812 @default.
• W62067653 cites W2023843746 @default.
• W62067653 cites W2024074211 @default.
• W62067653 cites W2024078974 @default.
• W62067653 cites W2024291694 @default.
• W62067653 cites W2024654143 @default.
• W62067653 cites W2025001402 @default.
• W62067653 cites W2025042121 @default.
• W62067653 cites W2025351604 @default.

• next