Matches in SemOpenAlex for { <https://semopenalex.org/work/W63763533> ?p ?o ?g. }
- W63763533 endingPage "6" @default.
- W63763533 startingPage "281" @default.
- W63763533 abstract "Morbidity caused by brain dysfunction affects more than 50 million persons in the United States. Although new neuropharmaceuticals have the potential for treating specific brain diseases, they may not effectively enter brain from blood. Safe strategies are needed for drug delivery through the brain capillary wall, which makes up the blood-brain barrier in vivo. Two of these strategies are reviewed, as are related new developments in the molecular and cell biology of the brain capillary endothelium. The production of chimeric peptides represents a physiologic-based strategy for drug delivery. It entails the covalent coupling of the neuropharmaceutical to a brain transport vector, allowing transportation through the blood-brain barrier. Another strategy is biochemical opening of the blood-brain barrier: intracarotid leukotriene infusion is a method for selectively increasing blood-brain barrier permeability in brain tumors without affecting barrier permeability in normal brain tissue." @default.
- W63763533 created "2016-06-24" @default.
- W63763533 creator A5000308279 @default.
- W63763533 creator A5012947810 @default.
- W63763533 creator A5019253871 @default.
- W63763533 creator A5027480548 @default.
- W63763533 date "1992-03-01" @default.
- W63763533 modified "2023-09-25" @default.
- W63763533 title "Blood-brain barrier and new approaches to brain drug delivery." @default.
- W63763533 cites W104371271 @default.
- W63763533 cites W109172496 @default.
- W63763533 cites W1501069255 @default.
- W63763533 cites W1692343830 @default.
- W63763533 cites W1956702905 @default.
- W63763533 cites W1971903700 @default.
- W63763533 cites W1973942903 @default.
- W63763533 cites W1975140802 @default.
- W63763533 cites W1980664953 @default.
- W63763533 cites W1983533408 @default.
- W63763533 cites W1984685689 @default.
- W63763533 cites W1985265289 @default.
- W63763533 cites W1985944040 @default.
- W63763533 cites W1987342201 @default.
- W63763533 cites W1991029054 @default.
- W63763533 cites W2003931073 @default.
- W63763533 cites W2005447528 @default.
- W63763533 cites W2010260282 @default.
- W63763533 cites W2015212543 @default.
- W63763533 cites W2023435913 @default.
- W63763533 cites W2024010463 @default.
- W63763533 cites W2044228427 @default.
- W63763533 cites W2048428129 @default.
- W63763533 cites W2054909845 @default.
- W63763533 cites W2055375115 @default.
- W63763533 cites W2061096622 @default.
- W63763533 cites W2062815587 @default.
- W63763533 cites W2063414748 @default.
- W63763533 cites W2065298888 @default.
- W63763533 cites W2066912376 @default.
- W63763533 cites W2069465707 @default.
- W63763533 cites W2071579783 @default.
- W63763533 cites W2074257360 @default.
- W63763533 cites W2074274244 @default.
- W63763533 cites W2075004701 @default.
- W63763533 cites W2078771482 @default.
- W63763533 cites W2080086992 @default.
- W63763533 cites W2083180717 @default.
- W63763533 cites W2088123456 @default.
- W63763533 cites W2088476270 @default.
- W63763533 cites W2088822897 @default.
- W63763533 cites W2089766043 @default.
- W63763533 cites W2089816465 @default.
- W63763533 cites W2090341475 @default.
- W63763533 cites W2095415294 @default.
- W63763533 cites W2108887091 @default.
- W63763533 cites W2110569992 @default.
- W63763533 cites W2152353759 @default.
- W63763533 cites W2155421201 @default.
- W63763533 cites W2167789139 @default.
- W63763533 cites W2171335844 @default.
- W63763533 cites W2216897043 @default.
- W63763533 cites W2261912426 @default.
- W63763533 cites W2271653357 @default.
- W63763533 cites W2289966244 @default.
- W63763533 cites W2314224390 @default.
- W63763533 cites W2402220659 @default.
- W63763533 cites W2415862357 @default.
- W63763533 cites W2418784160 @default.
- W63763533 cites W3024734494 @default.
- W63763533 cites W3105898142 @default.
- W63763533 cites W46005000 @default.
- W63763533 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1003235" @default.
- W63763533 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1595245" @default.
- W63763533 hasPublicationYear "1992" @default.
- W63763533 type Work @default.
- W63763533 sameAs 63763533 @default.
- W63763533 citedByCount "14" @default.
- W63763533 countsByYear W637635332012 @default.
- W63763533 countsByYear W637635332013 @default.
- W63763533 countsByYear W637635332014 @default.
- W63763533 countsByYear W637635332015 @default.
- W63763533 countsByYear W637635332022 @default.
- W63763533 crossrefType "journal-article" @default.
- W63763533 hasAuthorship W63763533A5000308279 @default.
- W63763533 hasAuthorship W63763533A5012947810 @default.
- W63763533 hasAuthorship W63763533A5019253871 @default.
- W63763533 hasAuthorship W63763533A5027480548 @default.
- W63763533 hasConcept C126322002 @default.
- W63763533 hasConcept C134728086 @default.
- W63763533 hasConcept C169760540 @default.
- W63763533 hasConcept C171250308 @default.
- W63763533 hasConcept C192562407 @default.
- W63763533 hasConcept C2778402981 @default.
- W63763533 hasConcept C2779820397 @default.
- W63763533 hasConcept C2780035454 @default.
- W63763533 hasConcept C529278444 @default.
- W63763533 hasConcept C71924100 @default.
- W63763533 hasConcept C86803240 @default.