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- W68716986 abstract "Hydroxyapatite fibers were prepared by a reaction of ion exchange of potassium alginate. To investigate the biocompatibility of the hydroxyapatite fibers, surface changes of these fibers were investigated in vitro and in vivo. In vitro experiment: the fibers were immersed in distilled water and a simulated body fluid (SBF) at 37°C for 9 weeks. After immersion, many voids were observed on the surface of the fibers in distilled water, whereas, the small flake-like particles precipitated on the surface of the fiber and the micro-pores were partially formed around the grain boundary in the SBF. In vivo experiment: diffusion chambers filled with these fibers were implanted in subcutaneous tissue of rats. At 3 weeks after implantation, small pores and granular precipitates were observed on the surface of the fibers covered with fascia. These results suggest that the hydroxyapatite fibers are useful biocompatible ceramics which are especially suitable for filling materials." @default.
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- W68716986 date "1994-01-01" @default.
- W68716986 modified "2023-09-27" @default.
- W68716986 title "Preparation of Hydroxyapatite Fiber by using Alginate and its Application to Bioceramics" @default.
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- W68716986 doi "https://doi.org/10.1016/b978-0-08-042144-5.50010-8" @default.
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