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- NCIT_C1004 IAO_0000115 "A piperidinedione antineoplaston with potential antineoplastic activity. Antineoplaston A10 was originally isolated from human urine but is now synthetically derived. This agent intercalates into DNA, resulting in cell cycle arrest in G1 phase, reduction of mitosis, and decreased protein synthesis. Antineoplaston A10 may also inhibit ras-oncogene expression and activate tumor suppressor gene p53, leading to cell differentiation and apoptosis. (NCI04)" @default.
- NCIT_C1004 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1004 NCIT_NHC0 "C1004" @default.
- NCIT_C1004 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C1004 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1004 NCIT_P108 "Antineoplaston A10" @default.
- NCIT_C1004 NCIT_P175 "377381" @default.
- NCIT_C1004 NCIT_P175 "619130" @default.
- NCIT_C1004 NCIT_P207 "C0052080" @default.
- NCIT_C1004 NCIT_P210 "91531-30-5" @default.
- NCIT_C1004 NCIT_P319 "16VY3TM7ZO" @default.
- NCIT_C1004 NCIT_P322 "FDA" @default.
- NCIT_C1004 NCIT_P322 "GDC" @default.
- NCIT_C1004 NCIT_P329 "41984" @default.
- NCIT_C1004 NCIT_P330 "41984" @default.
- NCIT_C1004 NCIT_P366 "Antineoplaston_A10" @default.
- NCIT_C1004 NCIT_P375 "Antineoplaston A10" @default.
- NCIT_C1004 NCIT_P399 "41984" @default.
- NCIT_C1004 normalizedInformationContent "92.730304365937428" @default.
- NCIT_C1004 referenceCount "3" @default.
- NCIT_C1004 hasExactSynonym "3-Phenylacetylamino-2, 6-piperidinedione" @default.
- NCIT_C1004 hasExactSynonym "3-Phenylacetylamino-2,6-piperidinedione" @default.
- NCIT_C1004 hasExactSynonym "A10" @default.
- NCIT_C1004 hasExactSynonym "ANTINEOPLASTON A10" @default.
- NCIT_C1004 hasExactSynonym "Antineoplaston A10" @default.
- NCIT_C1004 hasExactSynonym "Atengenal" @default.
- NCIT_C1004 hasExactSynonym "Benzeneacetamide, N-(2,6-dioxo-3-piperidinyl)-, (S)-" @default.
- NCIT_C1004 inSubset NCIT_C128784 @default.
- NCIT_C1004 inSubset NCIT_C157711 @default.
- NCIT_C1004 inSubset NCIT_C157712 @default.
- NCIT_C1004 inSubset NCIT_C176424 @default.
- NCIT_C1004 inSubset NCIT_C177537 @default.
- NCIT_C1004 inSubset NCIT_C63923 @default.
- NCIT_C1004 type Class @default.
- NCIT_C1004 isDefinedBy ncit.owl @default.
- NCIT_C1004 label "Antineoplaston A10" @default.
- NCIT_C1004 subClassOf NCIT_C1004 @default.
- NCIT_C1004 subClassOf NCIT_C1908 @default.
- NCIT_C1004 subClassOf NCIT_C1909 @default.
- NCIT_C1004 subClassOf NCIT_C1934 @default.
- NCIT_C1004 subClassOf NCIT_C2122 @default.
- NCIT_C1004 subClassOf NCIT_C2500 @default.
- NCIT_C1004 subClassOf NCIT_C274 @default.