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- NCIT_C1005 IAO_0000115 "A small-molecule arsenic compound with antineoplastic activity. The mechanism of action of arsenic trioxide is not completely understood. This agent causes damage to or degradation of the promyelocytic leukemia protein/retinoic acid receptor-alpha (PML/RARa) fusion protein; induces apoptosis in acute promyelocytic leukemia (APL) cells and in many other tumor cell types; promotes cell differentiation and suppresses cell proliferation in many different tumor cell types; and is pro-angiogenic. (NCI04)" @default.
- NCIT_C1005 NCIT_A24 NCIT_C274 @default.
- NCIT_C1005 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1005 NCIT_A7 NCIT_C53622 @default.
- NCIT_C1005 NCIT_NHC0 "C1005" @default.
- NCIT_C1005 NCIT_P106 "Inorganic Chemical" @default.
- NCIT_C1005 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1005 NCIT_P107 "Arsenic Trioxide" @default.
- NCIT_C1005 NCIT_P108 "Arsenic Trioxide" @default.
- NCIT_C1005 NCIT_P175 "706363" @default.
- NCIT_C1005 NCIT_P207 "C0052416" @default.
- NCIT_C1005 NCIT_P210 "1327-53-3" @default.
- NCIT_C1005 NCIT_P302 "Myelodysplastic syndrome; multiple myeloma; chronic myeloid leukemia; acute myelocytic leukemia" @default.
- NCIT_C1005 NCIT_P319 "S7V92P67HO" @default.
- NCIT_C1005 NCIT_P322 "CTRP" @default.
- NCIT_C1005 NCIT_P322 "FDA" @default.
- NCIT_C1005 NCIT_P322 "GDC" @default.
- NCIT_C1005 NCIT_P322 "PCDC" @default.
- NCIT_C1005 NCIT_P325 "A drug used to treat acute promyelocytic leukemia (APL) that has not gotten better or that has come back after treatment with other anticancer drugs. It is also being studied in the treatment of other types of cancer." @default.
- NCIT_C1005 NCIT_P329 "43067" @default.
- NCIT_C1005 NCIT_P330 "43067" @default.
- NCIT_C1005 NCIT_P350 "As2O3" @default.
- NCIT_C1005 NCIT_P366 "Arsenic_Trioxide" @default.
- NCIT_C1005 NCIT_P368 "CHEBI:30621" @default.
- NCIT_C1005 NCIT_P375 "Arsenic Trioxide" @default.
- NCIT_C1005 NCIT_P399 "43067" @default.
- NCIT_C1005 NCIT_R124 NCIT_C17710 @default.
- NCIT_C1005 NCIT_R124 NCIT_C17828 @default.
- NCIT_C1005 NCIT_R124 NCIT_C19986 @default.
- NCIT_C1005 NCIT_R124 NCIT_C40551 @default.
- NCIT_C1005 NCIT_R125 NCIT_C16399 @default.
- NCIT_C1005 NCIT_R125 NCIT_C17557 @default.
- NCIT_C1005 NCIT_R125 NCIT_C17828 @default.
- NCIT_C1005 NCIT_R125 NCIT_C17932 @default.
- NCIT_C1005 NCIT_R125 NCIT_C20480 @default.
- NCIT_C1005 NCIT_R125 NCIT_C21124 @default.
- NCIT_C1005 NCIT_R125 NCIT_C21128 @default.
- NCIT_C1005 NCIT_R125 NCIT_C21147 @default.
- NCIT_C1005 NCIT_R125 NCIT_C40738 @default.
- NCIT_C1005 NCIT_R125 NCIT_C41515 @default.
- NCIT_C1005 NCIT_R72 NCIT_C12219 @default.
- NCIT_C1005 NCIT_R72 NCIT_C13258 @default.
- NCIT_C1005 NCIT_R72 NCIT_C13269 @default.
- NCIT_C1005 NCIT_R72 NCIT_C32221 @default.
- NCIT_C1005 NCIT_R72 NCIT_C33089 @default.
- NCIT_C1005 NCIT_R72 NCIT_C34070 @default.
- NCIT_C1005 normalizedInformationContent "83.027314241919257" @default.
- NCIT_C1005 referenceCount "13" @default.
- NCIT_C1005 hasExactSynonym "ARSENIC TRIOXIDE" @default.
- NCIT_C1005 hasExactSynonym "ATO" @default.
- NCIT_C1005 hasExactSynonym "Arsenic (III) Oxide" @default.
- NCIT_C1005 hasExactSynonym "Arsenic Sesquioxide" @default.
- NCIT_C1005 hasExactSynonym "Arsenic Trioxide" @default.
- NCIT_C1005 hasExactSynonym "Arsenous Acid Anhydride" @default.
- NCIT_C1005 hasExactSynonym "Arsenous Acid" @default.
- NCIT_C1005 hasExactSynonym "Arsenous Oxide" @default.
- NCIT_C1005 hasExactSynonym "Trisenox" @default.
- NCIT_C1005 hasExactSynonym "White Arsenic" @default.
- NCIT_C1005 hasExactSynonym "arsenic trioxide" @default.
- NCIT_C1005 inSubset NCIT_C116977 @default.
- NCIT_C1005 inSubset NCIT_C116978 @default.
- NCIT_C1005 inSubset NCIT_C128784 @default.
- NCIT_C1005 inSubset NCIT_C157711 @default.
- NCIT_C1005 inSubset NCIT_C157712 @default.
- NCIT_C1005 inSubset NCIT_C173234 @default.
- NCIT_C1005 inSubset NCIT_C174019 @default.
- NCIT_C1005 inSubset NCIT_C176424 @default.
- NCIT_C1005 inSubset NCIT_C177537 @default.
- NCIT_C1005 inSubset NCIT_C63923 @default.
- NCIT_C1005 type Class @default.
- NCIT_C1005 isDefinedBy ncit.owl @default.
- NCIT_C1005 label "Arsenic Trioxide" @default.
- NCIT_C1005 subClassOf NCIT_C1005 @default.
- NCIT_C1005 subClassOf NCIT_C1908 @default.
- NCIT_C1005 subClassOf NCIT_C1909 @default.
- NCIT_C1005 subClassOf NCIT_C1934 @default.
- NCIT_C1005 subClassOf NCIT_C2122 @default.
- NCIT_C1005 subClassOf NCIT_C274 @default.
- NCIT_C1005 equivalentClass B88f9c94d3e3c365b8752acdbc6b60f8f @default.
- NCIT_C1005 equivalentClass Bab13a820fc48dec12a96fa4f8ec2e087 @default.