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- NCIT_C101520 IAO_0000115 "An orally bioavailable protein tyrosine kinase inhibitor for FMS-related tyrosine kinase 3 (FLT3; STK1) and stem cell factor receptor (SCFR; KIT), with potential antineoplastic activity. FLT3/KIT kinase inhibitor AKN-028 binds to and inhibits both the wild-type and mutated forms of FLT3 and SCFR. This may result in an inhibition of tumor cell proliferation in cancer cell types that overexpress these receptor tyrosine kinases." @default.
- NCIT_C101520 NCIT_A32 NCIT_C1909 @default.
- NCIT_C101520 NCIT_NHC0 "C101520" @default.
- NCIT_C101520 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C101520 NCIT_P108 "FLT3/KIT Kinase Inhibitor AKN-028" @default.
- NCIT_C101520 NCIT_P207 "C3852612" @default.
- NCIT_C101520 NCIT_P210 "1175017-90-9" @default.
- NCIT_C101520 NCIT_P319 "Y66IS3CS0R" @default.
- NCIT_C101520 NCIT_P322 "FDA" @default.
- NCIT_C101520 NCIT_P322 "GDC" @default.
- NCIT_C101520 NCIT_P329 "731885" @default.
- NCIT_C101520 NCIT_P330 "731885" @default.
- NCIT_C101520 NCIT_P375 "FLT3/KIT Kinase Inhibitor AKN-028" @default.
- NCIT_C101520 NCIT_P399 "731885" @default.
- NCIT_C101520 normalizedInformationContent "100" @default.
- NCIT_C101520 referenceCount "1" @default.
- NCIT_C101520 hasExactSynonym "AKN-028" @default.
- NCIT_C101520 hasExactSynonym "BVT-II" @default.
- NCIT_C101520 hasExactSynonym "FLT3/KIT Kinase Inhibitor AKN-028" @default.
- NCIT_C101520 inSubset NCIT_C128784 @default.
- NCIT_C101520 inSubset NCIT_C157711 @default.
- NCIT_C101520 inSubset NCIT_C157712 @default.
- NCIT_C101520 inSubset NCIT_C176424 @default.
- NCIT_C101520 inSubset NCIT_C177537 @default.
- NCIT_C101520 inSubset NCIT_C63923 @default.
- NCIT_C101520 type Class @default.
- NCIT_C101520 isDefinedBy ncit.owl @default.
- NCIT_C101520 label "FLT3/KIT Kinase Inhibitor AKN-028" @default.
- NCIT_C101520 subClassOf NCIT_C101520 @default.
- NCIT_C101520 subClassOf NCIT_C129824 @default.
- NCIT_C101520 subClassOf NCIT_C129825 @default.
- NCIT_C101520 subClassOf NCIT_C1404 @default.
- NCIT_C101520 subClassOf NCIT_C1908 @default.
- NCIT_C101520 subClassOf NCIT_C1909 @default.
- NCIT_C101520 subClassOf NCIT_C1967 @default.
- NCIT_C101520 subClassOf NCIT_C2189 @default.
- NCIT_C101520 subClassOf NCIT_C274 @default.
- NCIT_C101520 subClassOf NCIT_C471 @default.