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- NCIT_C102571 IAO_0000115 "A recombinant form of the endogenous human cytokine erythropoietin (EPO) with erythropoiesis-stimulating activity. Similar to EPO, epoetin zeta binds to and activates erythropoietin receptors on the surface of committed erythroid progenitors in the bone marrow resulting in their proliferation and differentiation into functional erythrocytes. This may enhance red blood cell counts and hemoglobin levels. Epoetin zeta differs from other epoetins in its glycosylation profile. EPO is a glycosylated polypeptide primarily produced by renal peritubular cells and its synthesis is regulated by a serum oxygenation feedback mechanism." @default.
- NCIT_C102571 NCIT_NHC0 "C102571" @default.
- NCIT_C102571 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C102571 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C102571 NCIT_P108 "Epoetin Zeta" @default.
- NCIT_C102571 NCIT_P207 "C1997870" @default.
- NCIT_C102571 NCIT_P210 "604802-70-2" @default.
- NCIT_C102571 NCIT_P302 "anemia due to chronic kidney disease (CKD); reduction of allogeneic red blood cell transfusions" @default.
- NCIT_C102571 NCIT_P329 "735936" @default.
- NCIT_C102571 NCIT_P330 "735936" @default.
- NCIT_C102571 NCIT_P399 "735936" @default.
- NCIT_C102571 NCIT_R124 NCIT_C17828 @default.
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- NCIT_C102571 NCIT_R125 NCIT_C17828 @default.
- NCIT_C102571 NCIT_R125 NCIT_C17937 @default.
- NCIT_C102571 NCIT_R125 NCIT_C18081 @default.
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- NCIT_C102571 NCIT_R125 NCIT_C19255 @default.
- NCIT_C102571 NCIT_R125 NCIT_C20480 @default.
- NCIT_C102571 NCIT_R125 NCIT_C20863 @default.
- NCIT_C102571 NCIT_R125 NCIT_C21124 @default.
- NCIT_C102571 NCIT_R125 NCIT_C21128 @default.
- NCIT_C102571 NCIT_R125 NCIT_C21147 @default.
- NCIT_C102571 NCIT_R125 NCIT_C26280 @default.
- NCIT_C102571 NCIT_R125 NCIT_C40739 @default.
- NCIT_C102571 NCIT_R125 NCIT_C40833 @default.
- NCIT_C102571 NCIT_R146 NCIT_C17021 @default.
- NCIT_C102571 NCIT_R146 NCIT_C17295 @default.
- NCIT_C102571 NCIT_R146 NCIT_C17393 @default.
- NCIT_C102571 NCIT_R146 NCIT_C17667 @default.
- NCIT_C102571 NCIT_R146 NCIT_C17728 @default.
- NCIT_C102571 NCIT_R146 NCIT_C18106 @default.
- NCIT_C102571 NCIT_R146 NCIT_C20027 @default.
- NCIT_C102571 NCIT_R146 NCIT_C26548 @default.
- NCIT_C102571 normalizedInformationContent "100" @default.
- NCIT_C102571 referenceCount "1" @default.
- NCIT_C102571 hasExactSynonym "Epoetin Zeta" @default.
- NCIT_C102571 hasExactSynonym "SB309" @default.
- NCIT_C102571 hasExactSynonym "Silapo" @default.
- NCIT_C102571 inSubset NCIT_C176424 @default.
- NCIT_C102571 type Class @default.
- NCIT_C102571 isDefinedBy ncit.owl @default.
- NCIT_C102571 label "Epoetin Zeta" @default.
- NCIT_C102571 subClassOf NCIT_C102571 @default.
- NCIT_C102571 subClassOf NCIT_C1908 @default.
- NCIT_C102571 subClassOf NCIT_C1909 @default.
- NCIT_C102571 subClassOf NCIT_C2395 @default.
- NCIT_C102571 subClassOf NCIT_C307 @default.
- NCIT_C102571 subClassOf NCIT_C477 @default.
- NCIT_C102571 subClassOf NCIT_C530 @default.