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- NCIT_C1026 IAO_0000115 "A macrocyclic lactone isolated from the bryozoan Bugula neritina with antineoplastic activity. Bryostatin 1 binds to and inhibits the cell-signaling enzyme protein kinase C, resulting in the inhibition of tumor cell proliferation, the promotion of tumor cell differentiation, and the induction of tumor cell apoptosis. This agent may act synergistically with other chemotherapeutic agents. (NCI04)" @default.
- NCIT_C1026 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1026 NCIT_A7 NCIT_C17017 @default.
- NCIT_C1026 NCIT_NHC0 "C1026" @default.
- NCIT_C1026 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1026 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1026 NCIT_P107 "Bryostatin 1" @default.
- NCIT_C1026 NCIT_P108 "Bryostatin 1" @default.
- NCIT_C1026 NCIT_P175 "339555" @default.
- NCIT_C1026 NCIT_P207 "C0054173" @default.
- NCIT_C1026 NCIT_P210 "83314-01-6" @default.
- NCIT_C1026 NCIT_P319 "37O2X55Y9E" @default.
- NCIT_C1026 NCIT_P322 "CTRP" @default.
- NCIT_C1026 NCIT_P322 "FDA" @default.
- NCIT_C1026 NCIT_P322 "GDC" @default.
- NCIT_C1026 NCIT_P325 "A substance being studied in the treatment of cancer and certain brain conditions such as Alzheimer disease and stroke. It binds to an enzyme involved in cell growth and it may help anticancer drugs work better. Bryostatin 1 comes from a marine organism. It is a type of protein kinase C modulator." @default.
- NCIT_C1026 NCIT_P329 "41959" @default.
- NCIT_C1026 NCIT_P330 "41959" @default.
- NCIT_C1026 NCIT_P350 "C47H68O17" @default.
- NCIT_C1026 NCIT_P366 "Bryostatin-1" @default.
- NCIT_C1026 NCIT_P375 "Bryostatin 1" @default.
- NCIT_C1026 NCIT_P399 "41959" @default.
- NCIT_C1026 NCIT_R124 NCIT_C17710 @default.
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- NCIT_C1026 NCIT_R124 NCIT_C28498 @default.
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- NCIT_C1026 NCIT_R125 NCIT_C17133 @default.
- NCIT_C1026 NCIT_R125 NCIT_C17828 @default.
- NCIT_C1026 NCIT_R125 NCIT_C18081 @default.
- NCIT_C1026 NCIT_R125 NCIT_C20150 @default.
- NCIT_C1026 NCIT_R125 NCIT_C20480 @default.
- NCIT_C1026 NCIT_R125 NCIT_C20751 @default.
- NCIT_C1026 NCIT_R125 NCIT_C40715 @default.
- NCIT_C1026 NCIT_R125 NCIT_C40738 @default.
- NCIT_C1026 NCIT_R125 NCIT_C40821 @default.
- NCIT_C1026 NCIT_R125 NCIT_C41515 @default.
- NCIT_C1026 NCIT_R125 NCIT_C51037 @default.
- NCIT_C1026 NCIT_R146 NCIT_C17017 @default.
- NCIT_C1026 NCIT_R146 NCIT_C21176 @default.
- NCIT_C1026 NCIT_R146 NCIT_C26548 @default.
- NCIT_C1026 normalizedInformationContent "83.556969816060246" @default.
- NCIT_C1026 referenceCount "12" @default.
- NCIT_C1026 hasExactSynonym "B705008K112" @default.
- NCIT_C1026 hasExactSynonym "BRYOSTATIN 1" @default.
- NCIT_C1026 hasExactSynonym "Bryostatin 1" @default.
- NCIT_C1026 hasExactSynonym "Bryostatin I" @default.
- NCIT_C1026 hasExactSynonym "bryostatin 1" @default.
- NCIT_C1026 inSubset NCIT_C116977 @default.
- NCIT_C1026 inSubset NCIT_C116978 @default.
- NCIT_C1026 inSubset NCIT_C128784 @default.
- NCIT_C1026 inSubset NCIT_C157711 @default.
- NCIT_C1026 inSubset NCIT_C157712 @default.
- NCIT_C1026 inSubset NCIT_C176424 @default.
- NCIT_C1026 inSubset NCIT_C177537 @default.
- NCIT_C1026 inSubset NCIT_C63923 @default.
- NCIT_C1026 type Class @default.
- NCIT_C1026 isDefinedBy ncit.owl @default.
- NCIT_C1026 label "Bryostatin 1" @default.
- NCIT_C1026 subClassOf NCIT_C1026 @default.
- NCIT_C1026 subClassOf NCIT_C1404 @default.
- NCIT_C1026 subClassOf NCIT_C1908 @default.
- NCIT_C1026 subClassOf NCIT_C1909 @default.
- NCIT_C1026 subClassOf NCIT_C2089 @default.
- NCIT_C1026 subClassOf NCIT_C471 @default.
- NCIT_C1026 subClassOf NCIT_C61074 @default.
- NCIT_C1026 equivalentClass B0d273719388963a65dc18c927ebc2d4b @default.
- NCIT_C1026 equivalentClass B435fc059610171ad55dbc137063ecdb6 @default.