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- NCIT_C102852 IAO_0000115 "An orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-angiogenic and antineoplastic activities. Upon oral administration, fruquintinib inhibits VEGF-induced phosphorylation of VEGFRs 1, 2, and 3 which may result in the inhibition of migration, proliferation and survival of endothelial cells, microvessel formation, the inhibition of tumor cell proliferation, and tumor cell death. Expression of VEGFRs may be upregulated in a variety of tumor cell types." @default.
- NCIT_C102852 NCIT_A32 NCIT_C1909 @default.
- NCIT_C102852 NCIT_A7 NCIT_C17975 @default.
- NCIT_C102852 NCIT_A7 NCIT_C26203 @default.
- NCIT_C102852 NCIT_A7 NCIT_C28496 @default.
- NCIT_C102852 NCIT_NHC0 "C102852" @default.
- NCIT_C102852 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C102852 NCIT_P107 "Fruquintinib" @default.
- NCIT_C102852 NCIT_P108 "Fruquintinib" @default.
- NCIT_C102852 NCIT_P207 "C3640967" @default.
- NCIT_C102852 NCIT_P210 "1194506-26-7" @default.
- NCIT_C102852 NCIT_P319 "49DXG3M5ZW" @default.
- NCIT_C102852 NCIT_P322 "CTRP" @default.
- NCIT_C102852 NCIT_P322 "FDA" @default.
- NCIT_C102852 NCIT_P322 "GDC" @default.
- NCIT_C102852 NCIT_P329 "737616" @default.
- NCIT_C102852 NCIT_P330 "737616" @default.
- NCIT_C102852 NCIT_P375 "Fruquintinib" @default.
- NCIT_C102852 NCIT_P399 "737616" @default.
- NCIT_C102852 normalizedInformationContent "100" @default.
- NCIT_C102852 referenceCount "1" @default.
- NCIT_C102852 hasExactSynonym "6-(6,7-Dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamide" @default.
- NCIT_C102852 hasExactSynonym "Elunate" @default.
- NCIT_C102852 hasExactSynonym "FRUQUINTINIB" @default.
- NCIT_C102852 hasExactSynonym "Fruquintinib" @default.
- NCIT_C102852 hasExactSynonym "HMPL-013" @default.
- NCIT_C102852 hasExactSynonym "VEGFR-1/2/3 Inhibitor HMPL-013" @default.
- NCIT_C102852 inSubset NCIT_C116977 @default.
- NCIT_C102852 inSubset NCIT_C116978 @default.
- NCIT_C102852 inSubset NCIT_C128784 @default.
- NCIT_C102852 inSubset NCIT_C157711 @default.
- NCIT_C102852 inSubset NCIT_C157712 @default.
- NCIT_C102852 inSubset NCIT_C176424 @default.
- NCIT_C102852 inSubset NCIT_C177537 @default.
- NCIT_C102852 inSubset NCIT_C63923 @default.
- NCIT_C102852 type Class @default.
- NCIT_C102852 isDefinedBy ncit.owl @default.
- NCIT_C102852 label "Fruquintinib" @default.
- NCIT_C102852 subClassOf NCIT_C102852 @default.
- NCIT_C102852 subClassOf NCIT_C129824 @default.
- NCIT_C102852 subClassOf NCIT_C129825 @default.
- NCIT_C102852 subClassOf NCIT_C1404 @default.
- NCIT_C102852 subClassOf NCIT_C163758 @default.
- NCIT_C102852 subClassOf NCIT_C163953 @default.
- NCIT_C102852 subClassOf NCIT_C1742 @default.
- NCIT_C102852 subClassOf NCIT_C1908 @default.
- NCIT_C102852 subClassOf NCIT_C1909 @default.
- NCIT_C102852 subClassOf NCIT_C1967 @default.
- NCIT_C102852 subClassOf NCIT_C2189 @default.
- NCIT_C102852 subClassOf NCIT_C274 @default.
- NCIT_C102852 subClassOf NCIT_C471 @default.
- NCIT_C102852 subClassOf NCIT_C93259 @default.