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- NCIT_C102976 IAO_0000115 "An orally bioavailable small molecule tyrosine kinase inhibitor that targets both Abl and Src kinases with potential antineoplastic activity. Upon oral administration, AZD0424 selectively inhibits both Src and Abl kinase activity which may result in the inhibition of tumor growth in susceptible tumor cells. Src and Abl kinases are upregulated in certain tumor cells and play important roles in tumor cell proliferation and metastasis." @default.
- NCIT_C102976 NCIT_A32 NCIT_C1909 @default.
- NCIT_C102976 NCIT_NHC0 "C102976" @default.
- NCIT_C102976 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C102976 NCIT_P108 "Src/Abl Kinase Inhibitor AZD0424" @default.
- NCIT_C102976 NCIT_P208 "CL437215" @default.
- NCIT_C102976 NCIT_P210 "692054-06-1" @default.
- NCIT_C102976 NCIT_P319 "642PS51324" @default.
- NCIT_C102976 NCIT_P322 "FDA" @default.
- NCIT_C102976 NCIT_P322 "GDC" @default.
- NCIT_C102976 NCIT_P329 "739328" @default.
- NCIT_C102976 NCIT_P330 "739328" @default.
- NCIT_C102976 NCIT_P375 "Src/Abl Kinase Inhibitor AZD0424" @default.
- NCIT_C102976 NCIT_P399 "739328" @default.
- NCIT_C102976 normalizedInformationContent "100" @default.
- NCIT_C102976 referenceCount "1" @default.
- NCIT_C102976 hasExactSynonym "AZD-0424" @default.
- NCIT_C102976 hasExactSynonym "AZD0424" @default.
- NCIT_C102976 hasExactSynonym "Src/Abl Kinase Inhibitor AZD0424" @default.
- NCIT_C102976 inSubset NCIT_C128784 @default.
- NCIT_C102976 inSubset NCIT_C157711 @default.
- NCIT_C102976 inSubset NCIT_C157712 @default.
- NCIT_C102976 inSubset NCIT_C176424 @default.
- NCIT_C102976 inSubset NCIT_C177537 @default.
- NCIT_C102976 inSubset NCIT_C63923 @default.
- NCIT_C102976 type Class @default.
- NCIT_C102976 isDefinedBy ncit.owl @default.
- NCIT_C102976 label "Src/Abl Kinase Inhibitor AZD0424" @default.
- NCIT_C102976 subClassOf NCIT_C102976 @default.
- NCIT_C102976 subClassOf NCIT_C129824 @default.
- NCIT_C102976 subClassOf NCIT_C129825 @default.
- NCIT_C102976 subClassOf NCIT_C1404 @default.
- NCIT_C102976 subClassOf NCIT_C1908 @default.
- NCIT_C102976 subClassOf NCIT_C1909 @default.
- NCIT_C102976 subClassOf NCIT_C1967 @default.
- NCIT_C102976 subClassOf NCIT_C2189 @default.
- NCIT_C102976 subClassOf NCIT_C274 @default.
- NCIT_C102976 subClassOf NCIT_C471 @default.