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- NCIT_C1037 IAO_0000115 "An agent derived from acetohydroxamic acid with potential antineoplastic activity. Caracemide inhibits ribonuclease reductase, resulting in decreased DNA synthesis and tumor growth; it also inhibits acetylcholinesterase. In vivo, caracemide contributes to the formation of the neurotoxin methyl isocyanate; this effect, along with the agent's acetylcholinesterase activity, may be responsible for the severe central nervous system toxicity observed in clinical trials. (NCI04)" @default.
- NCIT_C1037 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1037 NCIT_NHC0 "C1037" @default.
- NCIT_C1037 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1037 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1037 NCIT_P108 "Caracemide" @default.
- NCIT_C1037 NCIT_P175 "253272" @default.
- NCIT_C1037 NCIT_P207 "C0054633" @default.
- NCIT_C1037 NCIT_P210 "81424-67-1" @default.
- NCIT_C1037 NCIT_P319 "H74F6J185A" @default.
- NCIT_C1037 NCIT_P322 "FDA" @default.
- NCIT_C1037 NCIT_P322 "GDC" @default.
- NCIT_C1037 NCIT_P329 "39751" @default.
- NCIT_C1037 NCIT_P330 "39751" @default.
- NCIT_C1037 NCIT_P350 "C6H11N3O4" @default.
- NCIT_C1037 NCIT_P366 "Caracemide" @default.
- NCIT_C1037 NCIT_P375 "Caracemide" @default.
- NCIT_C1037 NCIT_P399 "39751" @default.
- NCIT_C1037 normalizedInformationContent "100" @default.
- NCIT_C1037 referenceCount "1" @default.
- NCIT_C1037 hasExactSynonym "Acetamide, N-[(Methylamino)carbonyl]-N-[[(methylamino)carbonyl]oxy]-(9CI)" @default.
- NCIT_C1037 hasExactSynonym "Acetamide, N-[(methylamino)carbonyl]-N-[[(methylamino)carbonyl]oxy]- (9CI)" @default.
- NCIT_C1037 hasExactSynonym "CARACEMIDE" @default.
- NCIT_C1037 hasExactSynonym "Caracemide" @default.
- NCIT_C1037 hasExactSynonym "N-Acetyl-N-(methylcarbamoyloxy)-N'-methylurea" @default.
- NCIT_C1037 inSubset NCIT_C128784 @default.
- NCIT_C1037 inSubset NCIT_C157711 @default.
- NCIT_C1037 inSubset NCIT_C157712 @default.
- NCIT_C1037 inSubset NCIT_C176424 @default.
- NCIT_C1037 inSubset NCIT_C177537 @default.
- NCIT_C1037 inSubset NCIT_C63923 @default.
- NCIT_C1037 type Class @default.
- NCIT_C1037 isDefinedBy ncit.owl @default.
- NCIT_C1037 label "Caracemide" @default.
- NCIT_C1037 subClassOf NCIT_C1037 @default.
- NCIT_C1037 subClassOf NCIT_C1908 @default.
- NCIT_C1037 subClassOf NCIT_C1909 @default.
- NCIT_C1037 subClassOf NCIT_C2150 @default.
- NCIT_C1037 subClassOf NCIT_C471 @default.