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- NCIT_C1049 IAO_0000115 "A glucose-linked chloroethylnitrosourea with potential antineoplastic activity. Chlorozotocin alkylates DNA and proteins, induces the formation of interstrand DNA and DNA-protein crosslinks, and causes DNA strand breakage, thereby damaging DNA and resulting in cell death. This agent has been shown to exhibit antitumor and immunomodulatory effects in cell lines and animal models. Chlorozotocin is a mutagen and is less myelotoxic than other nitrosoureas. (NCI04)" @default.
- NCIT_C1049 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1049 NCIT_NHC0 "C1049" @default.
- NCIT_C1049 NCIT_P106 "Antibiotic" @default.
- NCIT_C1049 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1049 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1049 NCIT_P108 "Chlorozotocin" @default.
- NCIT_C1049 NCIT_P175 "178248" @default.
- NCIT_C1049 NCIT_P207 "C0055465" @default.
- NCIT_C1049 NCIT_P210 "54749-90-5" @default.
- NCIT_C1049 NCIT_P319 "3053LTY75Z" @default.
- NCIT_C1049 NCIT_P322 "FDA" @default.
- NCIT_C1049 NCIT_P322 "GDC" @default.
- NCIT_C1049 NCIT_P329 "39182" @default.
- NCIT_C1049 NCIT_P330 "39182" @default.
- NCIT_C1049 NCIT_P350 "C9H16ClN3O7" @default.
- NCIT_C1049 NCIT_P366 "Chlorozotocin" @default.
- NCIT_C1049 NCIT_P375 "Chlorozotocin" @default.
- NCIT_C1049 NCIT_P399 "39182" @default.
- NCIT_C1049 normalizedInformationContent "100" @default.
- NCIT_C1049 referenceCount "1" @default.
- NCIT_C1049 hasExactSynonym "1-(2-chloroethyl)-1-nitroso-3-(D-glucos-2-yl)urea" @default.
- NCIT_C1049 hasExactSynonym "2-[3-(2-chloroethyl)-3-nitrosoureido]-2-deoxy-D-glucopyranose" @default.
- NCIT_C1049 hasExactSynonym "2-[[[(2-chloroethyl)nitrosamino]carbonyl]amino]-2-deoxy-D-glucose" @default.
- NCIT_C1049 hasExactSynonym "CHLOROZOTOCIN" @default.
- NCIT_C1049 hasExactSynonym "CHLZ" @default.
- NCIT_C1049 hasExactSynonym "CZT" @default.
- NCIT_C1049 hasExactSynonym "Chlorozotocin" @default.
- NCIT_C1049 hasExactSynonym "Chlorozotocyna" @default.
- NCIT_C1049 hasExactSynonym "D-Glucopyranose, 2-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]-2-deoxy-" @default.
- NCIT_C1049 hasExactSynonym "D-Glucose, 2-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]-2-deoxy- (9CI)" @default.
- NCIT_C1049 hasExactSynonym "D-glucopyranose, 2-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]-2-deoxy" @default.
- NCIT_C1049 hasExactSynonym "D-glucose, 2-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]-2-deoxy- (9CI)" @default.
- NCIT_C1049 hasExactSynonym "DCNU" @default.
- NCIT_C1049 inSubset NCIT_C128784 @default.
- NCIT_C1049 inSubset NCIT_C157711 @default.
- NCIT_C1049 inSubset NCIT_C157712 @default.
- NCIT_C1049 inSubset NCIT_C176424 @default.
- NCIT_C1049 inSubset NCIT_C177537 @default.
- NCIT_C1049 inSubset NCIT_C63923 @default.
- NCIT_C1049 type Class @default.
- NCIT_C1049 isDefinedBy ncit.owl @default.
- NCIT_C1049 label "Chlorozotocin" @default.
- NCIT_C1049 subClassOf NCIT_C1049 @default.
- NCIT_C1049 subClassOf NCIT_C1590 @default.
- NCIT_C1049 subClassOf NCIT_C186664 @default.
- NCIT_C1049 subClassOf NCIT_C1908 @default.
- NCIT_C1049 subClassOf NCIT_C1909 @default.
- NCIT_C1049 subClassOf NCIT_C274 @default.
- NCIT_C1049 subClassOf NCIT_C2842 @default.
- NCIT_C1049 subClassOf NCIT_C699 @default.