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- NCIT_C1096 IAO_0000115 "An orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is phosphorylated by deoxycytidine kinase to a triphosphate form which competes with thymidine for incorporation into DNA; its incorporation into DNA inhibits DNA synthesis, resulting in tumor cell death and tumor necrosis. The presence of deoxycytidine kinase in a tumor is a determinant of tumor sensitivity to this drug. (NCI04)" @default.
- NCIT_C1096 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1096 NCIT_NHC0 "C1096" @default.
- NCIT_C1096 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1096 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1096 NCIT_P108 "Fazarabine" @default.
- NCIT_C1096 NCIT_P175 "281272" @default.
- NCIT_C1096 NCIT_P207 "C0060103" @default.
- NCIT_C1096 NCIT_P210 "65886-71-7" @default.
- NCIT_C1096 NCIT_P319 "5V71D8JOKK" @default.
- NCIT_C1096 NCIT_P322 "FDA" @default.
- NCIT_C1096 NCIT_P322 "GDC" @default.
- NCIT_C1096 NCIT_P325 "An anticancer drug that is a type of antimetabolite." @default.
- NCIT_C1096 NCIT_P329 "40564" @default.
- NCIT_C1096 NCIT_P330 "40564" @default.
- NCIT_C1096 NCIT_P350 "C8H12N4O5" @default.
- NCIT_C1096 NCIT_P366 "Fazarabine" @default.
- NCIT_C1096 NCIT_P375 "Fazarabine" @default.
- NCIT_C1096 NCIT_P399 "40564" @default.
- NCIT_C1096 NCIT_R124 NCIT_C17710 @default.
- NCIT_C1096 NCIT_R124 NCIT_C17828 @default.
- NCIT_C1096 NCIT_R124 NCIT_C19899 @default.
- NCIT_C1096 NCIT_R124 NCIT_C34072 @default.
- NCIT_C1096 NCIT_R124 NCIT_C45556 @default.
- NCIT_C1096 NCIT_R125 NCIT_C17710 @default.
- NCIT_C1096 NCIT_R125 NCIT_C17828 @default.
- NCIT_C1096 NCIT_R125 NCIT_C18125 @default.
- NCIT_C1096 NCIT_R125 NCIT_C21080 @default.
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- NCIT_C1096 NCIT_R125 NCIT_C40664 @default.
- NCIT_C1096 NCIT_R125 NCIT_C41543 @default.
- NCIT_C1096 NCIT_R146 NCIT_C16554 @default.
- NCIT_C1096 NCIT_R146 NCIT_C16925 @default.
- NCIT_C1096 NCIT_R146 NCIT_C16984 @default.
- NCIT_C1096 NCIT_R146 NCIT_C17021 @default.
- NCIT_C1096 NCIT_R146 NCIT_C17210 @default.
- NCIT_C1096 NCIT_R146 NCIT_C19172 @default.
- NCIT_C1096 NCIT_R146 NCIT_C20027 @default.
- NCIT_C1096 NCIT_R146 NCIT_C20636 @default.
- NCIT_C1096 NCIT_R146 NCIT_C26548 @default.
- NCIT_C1096 normalizedInformationContent "95.413332725061409" @default.
- NCIT_C1096 referenceCount "2" @default.
- NCIT_C1096 hasExactSynonym "1,3, 5-Triazin-2(1H)-one, 4-Amino-1-beta-D- arabinofuranosyl- (9CI)" @default.
- NCIT_C1096 hasExactSynonym "1,3, 5-Triazin-2(1H)-one, 4-amino-1-.beta.-D- arabinofuranosyl- (9CI)" @default.
- NCIT_C1096 hasExactSynonym "1-.beta.-D-Arabinofuranosyl-5-azacytosine" @default.
- NCIT_C1096 hasExactSynonym "1-Beta-D-arabinofuranosyl-5-azacytosine" @default.
- NCIT_C1096 hasExactSynonym "Ara AC" @default.
- NCIT_C1096 hasExactSynonym "FAZARABINE" @default.
- NCIT_C1096 hasExactSynonym "Fazarabine" @default.
- NCIT_C1096 hasExactSynonym "Kymarabine" @default.
- NCIT_C1096 hasExactSynonym "ara-AC" @default.
- NCIT_C1096 hasExactSynonym "fazarabine" @default.
- NCIT_C1096 inSubset NCIT_C128784 @default.
- NCIT_C1096 inSubset NCIT_C157711 @default.
- NCIT_C1096 inSubset NCIT_C157712 @default.
- NCIT_C1096 inSubset NCIT_C176424 @default.
- NCIT_C1096 inSubset NCIT_C177537 @default.
- NCIT_C1096 inSubset NCIT_C63923 @default.
- NCIT_C1096 type Class @default.
- NCIT_C1096 isDefinedBy ncit.owl @default.
- NCIT_C1096 label "Fazarabine" @default.
- NCIT_C1096 subClassOf NCIT_C1096 @default.
- NCIT_C1096 subClassOf NCIT_C1557 @default.
- NCIT_C1096 subClassOf NCIT_C186664 @default.
- NCIT_C1096 subClassOf NCIT_C1908 @default.
- NCIT_C1096 subClassOf NCIT_C1909 @default.
- NCIT_C1096 subClassOf NCIT_C272 @default.
- NCIT_C1096 subClassOf NCIT_C274 @default.
- NCIT_C1096 equivalentClass B88fe1eccffe5dba791f463b273111aaf @default.
- NCIT_C1096 equivalentClass B9a4e170036ac709e2f6c02a053862fe0 @default.