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- NCIT_C1097 IAO_0000115 "An irreversible steroidal aromatase inhibitor, with antiestrogen and antineoplastic activities. Upon oral administration, exemestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the peripheral aromatization of androgens, including androstenedione and testosterone, to estrogens. This lowers estrogen levels in the blood circulation." @default.
- NCIT_C1097 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1097 NCIT_A7 NCIT_C16307 @default.
- NCIT_C1097 NCIT_NHC0 "C1097" @default.
- NCIT_C1097 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1097 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1097 NCIT_P107 "Exemestane" @default.
- NCIT_C1097 NCIT_P108 "Exemestane" @default.
- NCIT_C1097 NCIT_P175 "713563" @default.
- NCIT_C1097 NCIT_P207 "C0851344" @default.
- NCIT_C1097 NCIT_P210 "107868-30-4" @default.
- NCIT_C1097 NCIT_P302 "Estrogen Receptor-Positive Early Breast Cancer; early and advanced-stage breast cancer" @default.
- NCIT_C1097 NCIT_P319 "NY22HMQ4BX" @default.
- NCIT_C1097 NCIT_P322 "CTRP" @default.
- NCIT_C1097 NCIT_P322 "FDA" @default.
- NCIT_C1097 NCIT_P322 "GDC" @default.
- NCIT_C1097 NCIT_P325 "A drug used to treat advanced breast cancer and to prevent recurrent breast cancer in postmenopausal women who have already been treated with tamoxifen. It is also being studied in the treatment of other types of cancer. Aromasin causes a decrease in the amount of estrogen made by the body. It is a type of aromatase inhibitor." @default.
- NCIT_C1097 NCIT_P329 "42297" @default.
- NCIT_C1097 NCIT_P330 "42297" @default.
- NCIT_C1097 NCIT_P350 "C20H24O2" @default.
- NCIT_C1097 NCIT_P366 "Exemestane" @default.
- NCIT_C1097 NCIT_P368 "CHEBI:4953" @default.
- NCIT_C1097 NCIT_P375 "Exemestane" @default.
- NCIT_C1097 NCIT_P399 "42297" @default.
- NCIT_C1097 normalizedInformationContent "81.653330900245635" @default.
- NCIT_C1097 referenceCount "16" @default.
- NCIT_C1097 hasExactSynonym "6-Methyleneandrosta-1,4-diene-3,17-dione" @default.
- NCIT_C1097 hasExactSynonym "Aromasin" @default.
- NCIT_C1097 hasExactSynonym "EXEMESTANE" @default.
- NCIT_C1097 hasExactSynonym "Exemestane" @default.
- NCIT_C1097 hasExactSynonym "FCE-24304" @default.
- NCIT_C1097 hasExactSynonym "exemestane" @default.
- NCIT_C1097 inSubset NCIT_C116977 @default.
- NCIT_C1097 inSubset NCIT_C116978 @default.
- NCIT_C1097 inSubset NCIT_C128784 @default.
- NCIT_C1097 inSubset NCIT_C157711 @default.
- NCIT_C1097 inSubset NCIT_C157712 @default.
- NCIT_C1097 inSubset NCIT_C176424 @default.
- NCIT_C1097 inSubset NCIT_C177537 @default.
- NCIT_C1097 inSubset NCIT_C63923 @default.
- NCIT_C1097 type Class @default.
- NCIT_C1097 isDefinedBy ncit.owl @default.
- NCIT_C1097 label "Exemestane" @default.
- NCIT_C1097 subClassOf NCIT_C1097 @default.
- NCIT_C1097 subClassOf NCIT_C129818 @default.
- NCIT_C1097 subClassOf NCIT_C129824 @default.
- NCIT_C1097 subClassOf NCIT_C129825 @default.
- NCIT_C1097 subClassOf NCIT_C147908 @default.
- NCIT_C1097 subClassOf NCIT_C163758 @default.
- NCIT_C1097 subClassOf NCIT_C1740 @default.
- NCIT_C1097 subClassOf NCIT_C1908 @default.
- NCIT_C1097 subClassOf NCIT_C1909 @default.
- NCIT_C1097 subClassOf NCIT_C2017 @default.
- NCIT_C1097 subClassOf NCIT_C2189 @default.
- NCIT_C1097 subClassOf NCIT_C274 @default.
- NCIT_C1097 subClassOf NCIT_C471 @default.
- NCIT_C1097 subClassOf NCIT_C481 @default.
- NCIT_C1097 subClassOf NCIT_C547 @default.