Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C1103> ?p ?o ?g. }
Showing items 1 to 49 of
49
with 100 items per page.
- NCIT_C1103 IAO_0000115 "The acetate salt of a synthetic fluorinated corticosteroid with antiinflammatory and antiallergic activities. As a glucocorticoid-receptor agonist, fludrocortisone binds to cytoplasmic receptors, translocates to the nucleus, and subsequently initiates the transcription of glucocorticoid-responsive genes such as lipocortins to inhibit phospholipase A2 (PLA2). Inhibition of PLA2 activity prevents the release of arachidonic acid, a precursor of eicosanoids such as prostaglandins and leukotrienes; eicosanoids are important mediators in the pro-inflammatory response mechanism. As a mineralocorticoid-receptor agonist, this agent stimulates Na+ reabsorption and water retention and K+ and H+ secretion in the distal tubules and collecting ducts of the kidney." @default.
- NCIT_C1103 NCIT_NHC0 "C1103" @default.
- NCIT_C1103 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1103 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1103 NCIT_P108 "Fludrocortisone Acetate" @default.
- NCIT_C1103 NCIT_P175 "15186" @default.
- NCIT_C1103 NCIT_P207 "C0616274" @default.
- NCIT_C1103 NCIT_P210 "514-36-3" @default.
- NCIT_C1103 NCIT_P319 "V47IF0PVH4" @default.
- NCIT_C1103 NCIT_P322 "FDA" @default.
- NCIT_C1103 NCIT_P329 "39243" @default.
- NCIT_C1103 NCIT_P330 "39243" @default.
- NCIT_C1103 NCIT_P350 "C23H31FO6" @default.
- NCIT_C1103 NCIT_P366 "Fludrocortisone" @default.
- NCIT_C1103 NCIT_P399 "39243" @default.
- NCIT_C1103 NCIT_R122 NCIT_C16484 @default.
- NCIT_C1103 NCIT_R122 NCIT_C16486 @default.
- NCIT_C1103 NCIT_R122 NCIT_C16554 @default.
- NCIT_C1103 NCIT_R122 NCIT_C16865 @default.
- NCIT_C1103 NCIT_R122 NCIT_C16946 @default.
- NCIT_C1103 NCIT_R122 NCIT_C17021 @default.
- NCIT_C1103 NCIT_R122 NCIT_C17573 @default.
- NCIT_C1103 NCIT_R122 NCIT_C20027 @default.
- NCIT_C1103 NCIT_R122 NCIT_C26548 @default.
- NCIT_C1103 NCIT_R122 NCIT_C28459 @default.
- NCIT_C1103 normalizedInformationContent "100" @default.
- NCIT_C1103 referenceCount "1" @default.
- NCIT_C1103 hasExactSynonym "FLUDROCORTISONE ACETATE" @default.
- NCIT_C1103 hasExactSynonym "Florinef Acetate" @default.
- NCIT_C1103 hasExactSynonym "Florinef acetate" @default.
- NCIT_C1103 hasExactSynonym "Florinef" @default.
- NCIT_C1103 hasExactSynonym "Fludrocortisone Acetate" @default.
- NCIT_C1103 hasExactSynonym "Fludrocortisone acetate" @default.
- NCIT_C1103 inSubset NCIT_C176424 @default.
- NCIT_C1103 inSubset NCIT_C63923 @default.
- NCIT_C1103 type Class @default.
- NCIT_C1103 isDefinedBy ncit.owl @default.
- NCIT_C1103 label "Fludrocortisone Acetate" @default.
- NCIT_C1103 subClassOf NCIT_C1103 @default.
- NCIT_C1103 subClassOf NCIT_C147908 @default.
- NCIT_C1103 subClassOf NCIT_C1636 @default.
- NCIT_C1103 subClassOf NCIT_C1908 @default.
- NCIT_C1103 subClassOf NCIT_C1909 @default.
- NCIT_C1103 subClassOf NCIT_C211 @default.
- NCIT_C1103 subClassOf NCIT_C2364 @default.
- NCIT_C1103 subClassOf NCIT_C308 @default.
- NCIT_C1103 subClassOf NCIT_C521 @default.
- NCIT_C1103 subClassOf NCIT_C548 @default.
- NCIT_C1103 subClassOf NCIT_C574 @default.