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- NCIT_C1106 IAO_0000115 "A chloroethylating nitrosourea with antineoplastic activity. Fotemustine alkylates guanine by forming chloroethyl adducts at the 6 position of guanine, resulting in N1-guanine and N3-cytosine cross linkages, inhibition of DNA synthesis, cell cycle arrest, and finally apoptosis. This agent is lipophilic and crosses the blood-brain barrier." @default.
- NCIT_C1106 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1106 NCIT_NHC0 "C1106" @default.
- NCIT_C1106 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1106 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1106 NCIT_P108 "Fotemustine" @default.
- NCIT_C1106 NCIT_P207 "C0060696" @default.
- NCIT_C1106 NCIT_P210 "92118-27-9" @default.
- NCIT_C1106 NCIT_P319 "GQ7JL9P5I2" @default.
- NCIT_C1106 NCIT_P322 "FDA" @default.
- NCIT_C1106 NCIT_P322 "GDC" @default.
- NCIT_C1106 NCIT_P325 "A substance being studied in the treatment of brain tumors and metastatic melanoma of the eye. It is a type of nitrosourea." @default.
- NCIT_C1106 NCIT_P329 "38865" @default.
- NCIT_C1106 NCIT_P330 "38865" @default.
- NCIT_C1106 NCIT_P350 "C9H19ClN3O5P" @default.
- NCIT_C1106 NCIT_P366 "Fotemustine" @default.
- NCIT_C1106 NCIT_P375 "Fotemustine" @default.
- NCIT_C1106 NCIT_P399 "38865" @default.
- NCIT_C1106 normalizedInformationContent "100" @default.
- NCIT_C1106 referenceCount "1" @default.
- NCIT_C1106 hasExactSynonym "1-[N-(2-chloroethyl)-N-nitrosoureido]ethylphosphonic acid diethyl ester" @default.
- NCIT_C1106 hasExactSynonym "FOTEMUSTINE" @default.
- NCIT_C1106 hasExactSynonym "Fotemustine" @default.
- NCIT_C1106 hasExactSynonym "Muphoran" @default.
- NCIT_C1106 hasExactSynonym "S 10036" @default.
- NCIT_C1106 hasExactSynonym "[1-[[[(2-chloroethyl)nitrosamino]-carbonyl]amino]ethyl]phosphonic acid diethyl ester" @default.
- NCIT_C1106 hasExactSynonym "diethyl[1-[3-(2-chloroethyl)-3-nitrosoureido]ethyl]phosphonate" @default.
- NCIT_C1106 hasExactSynonym "fotemustine" @default.
- NCIT_C1106 inSubset NCIT_C128784 @default.
- NCIT_C1106 inSubset NCIT_C157711 @default.
- NCIT_C1106 inSubset NCIT_C157712 @default.
- NCIT_C1106 inSubset NCIT_C176424 @default.
- NCIT_C1106 inSubset NCIT_C177537 @default.
- NCIT_C1106 inSubset NCIT_C63923 @default.
- NCIT_C1106 type Class @default.
- NCIT_C1106 isDefinedBy ncit.owl @default.
- NCIT_C1106 label "Fotemustine" @default.
- NCIT_C1106 subClassOf NCIT_C1106 @default.
- NCIT_C1106 subClassOf NCIT_C1590 @default.
- NCIT_C1106 subClassOf NCIT_C186664 @default.
- NCIT_C1106 subClassOf NCIT_C1908 @default.
- NCIT_C1106 subClassOf NCIT_C1909 @default.
- NCIT_C1106 subClassOf NCIT_C274 @default.
- NCIT_C1106 subClassOf NCIT_C2842 @default.
- NCIT_C1106 subClassOf NCIT_C699 @default.