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- NCIT_C1230 IAO_0000115 "A water soluble salt and reducing agent that reacts with oxidizing agents. Although its exact mechanism of action is unknown, thiosulfate likely provides an exogenous source of sulfur, thereby hastening the detoxification of cyanide through the enzyme rhodanese (thiosulfate cyanide sulfurtransferase) which converts cyanide to the relatively nontoxic, excretable thiocyanate ion. In addition, this agent neutralizes the reactive alkylating species of nitrogen mustard, thereby decreasing skin toxicity related to nitrogen mustard extravasation. (NCI04)" @default.
- NCIT_C1230 NCIT_A33 NCIT_C70902 @default.
- NCIT_C1230 NCIT_NHC0 "C1230" @default.
- NCIT_C1230 NCIT_P106 "Inorganic Chemical" @default.
- NCIT_C1230 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1230 NCIT_P107 "Sodium Thiosulfate" @default.
- NCIT_C1230 NCIT_P108 "Sodium Thiosulfate" @default.
- NCIT_C1230 NCIT_P175 "45624" @default.
- NCIT_C1230 NCIT_P207 "C0074774" @default.
- NCIT_C1230 NCIT_P210 "10102-17-7" @default.
- NCIT_C1230 NCIT_P302 "Cisplatin-induced nephrotoxicity; Nitrogen mustard-induced skin toxicity, neutralizer; Poisoning, arsenic and cyanide" @default.
- NCIT_C1230 NCIT_P319 "HX1032V43M" @default.
- NCIT_C1230 NCIT_P322 "CTRP" @default.
- NCIT_C1230 NCIT_P322 "FDA" @default.
- NCIT_C1230 NCIT_P322 "PCDC" @default.
- NCIT_C1230 NCIT_P325 "A substance that is used in medicine as an antidote to cyanide poisoning and to decrease side effects of the anticancer drug cisplatin." @default.
- NCIT_C1230 NCIT_P329 "39602" @default.
- NCIT_C1230 NCIT_P330 "39602" @default.
- NCIT_C1230 NCIT_P350 "2Na.O3S2.5H2O" @default.
- NCIT_C1230 NCIT_P366 "Sodium_Thiosulfate" @default.
- NCIT_C1230 NCIT_P368 "CHEBI:32150" @default.
- NCIT_C1230 NCIT_P399 "39602" @default.
- NCIT_C1230 normalizedInformationContent "89.350088392419622" @default.
- NCIT_C1230 referenceCount "5" @default.
- NCIT_C1230 hasExactSynonym "Cyanide Antidote Package" @default.
- NCIT_C1230 hasExactSynonym "Disodium Thiosulfate" @default.
- NCIT_C1230 hasExactSynonym "Disodium thiosulfate" @default.
- NCIT_C1230 hasExactSynonym "S-Hydril" @default.
- NCIT_C1230 hasExactSynonym "SODIUM THIOSULFATE" @default.
- NCIT_C1230 hasExactSynonym "Sodium Hyposulfate" @default.
- NCIT_C1230 hasExactSynonym "Sodium Thiosulfate Pentahydrate" @default.
- NCIT_C1230 hasExactSynonym "Sodium Thiosulfate" @default.
- NCIT_C1230 hasExactSynonym "Sodium Thiosulphate" @default.
- NCIT_C1230 hasExactSynonym "Sodium thiosulfate" @default.
- NCIT_C1230 hasExactSynonym "Sodothiol" @default.
- NCIT_C1230 hasExactSynonym "Thiosulfate, Sodium, Pentahydrate" @default.
- NCIT_C1230 hasExactSynonym "Thiosulfuric Acid Disodium Salt" @default.
- NCIT_C1230 hasExactSynonym "Thiosulfuric acid disodium salt" @default.
- NCIT_C1230 hasExactSynonym "sodium thiosulfate" @default.
- NCIT_C1230 inSubset NCIT_C116977 @default.
- NCIT_C1230 inSubset NCIT_C116978 @default.
- NCIT_C1230 inSubset NCIT_C176424 @default.
- NCIT_C1230 inSubset NCIT_C177383 @default.
- NCIT_C1230 inSubset NCIT_C177404 @default.
- NCIT_C1230 inSubset NCIT_C63923 @default.
- NCIT_C1230 type Class @default.
- NCIT_C1230 isDefinedBy ncit.owl @default.
- NCIT_C1230 label "Sodium Thiosulfate" @default.
- NCIT_C1230 subClassOf NCIT_C1230 @default.
- NCIT_C1230 subClassOf NCIT_C1908 @default.
- NCIT_C1230 subClassOf NCIT_C1909 @default.
- NCIT_C1230 subClassOf NCIT_C26170 @default.