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- NCIT_C1306 IAO_0000115 "A guanine analogue with antineoplastic activity. O6-benzylguanine binds the DNA repair enzyme O(6)-alkylguanine DNA alkyltransferase (AGT), transferring the benzyl moiety to the active-site cysteine and resulting in inhibition of AGT-mediated DNA repair. Co-administration of this agent potentiates the effects of other chemotherapeutic agents that damage DNA. (NCI04)" @default.
- NCIT_C1306 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1306 NCIT_A7 NCIT_C17315 @default.
- NCIT_C1306 NCIT_NHC0 "C1306" @default.
- NCIT_C1306 NCIT_P106 "Nucleic Acid, Nucleoside, or Nucleotide" @default.
- NCIT_C1306 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1306 NCIT_P107 "O6-Benzylguanine" @default.
- NCIT_C1306 NCIT_P108 "O6-Benzylguanine" @default.
- NCIT_C1306 NCIT_P175 "637037" @default.
- NCIT_C1306 NCIT_P207 "C0083812" @default.
- NCIT_C1306 NCIT_P210 "19916-73-5" @default.
- NCIT_C1306 NCIT_P319 "01KC87F8FE" @default.
- NCIT_C1306 NCIT_P322 "CTRP" @default.
- NCIT_C1306 NCIT_P322 "FDA" @default.
- NCIT_C1306 NCIT_P322 "GDC" @default.
- NCIT_C1306 NCIT_P325 "A drug that may improve the response of cancer cells to chemotherapy." @default.
- NCIT_C1306 NCIT_P329 "42113" @default.
- NCIT_C1306 NCIT_P330 "42113" @default.
- NCIT_C1306 NCIT_P350 "C12H11N5O" @default.
- NCIT_C1306 NCIT_P366 "O_6_Benzylguanine" @default.
- NCIT_C1306 NCIT_P375 "O6-Benzylguanine" @default.
- NCIT_C1306 NCIT_P399 "42113" @default.
- NCIT_C1306 NCIT_R124 NCIT_C17710 @default.
- NCIT_C1306 NCIT_R124 NCIT_C17828 @default.
- NCIT_C1306 NCIT_R124 NCIT_C28498 @default.
- NCIT_C1306 NCIT_R124 NCIT_C40576 @default.
- NCIT_C1306 NCIT_R124 NCIT_C40577 @default.
- NCIT_C1306 NCIT_R125 NCIT_C16513 @default.
- NCIT_C1306 NCIT_R125 NCIT_C17710 @default.
- NCIT_C1306 NCIT_R125 NCIT_C17828 @default.
- NCIT_C1306 NCIT_R125 NCIT_C18300 @default.
- NCIT_C1306 NCIT_R125 NCIT_C28498 @default.
- NCIT_C1306 NCIT_R125 NCIT_C40661 @default.
- NCIT_C1306 NCIT_R125 NCIT_C41543 @default.
- NCIT_C1306 NCIT_R146 NCIT_C16554 @default.
- NCIT_C1306 NCIT_R146 NCIT_C17021 @default.
- NCIT_C1306 NCIT_R146 NCIT_C17210 @default.
- NCIT_C1306 NCIT_R146 NCIT_C20027 @default.
- NCIT_C1306 NCIT_R146 NCIT_C20075 @default.
- NCIT_C1306 NCIT_R146 NCIT_C26548 @default.
- NCIT_C1306 normalizedInformationContent "90.826665450122817" @default.
- NCIT_C1306 referenceCount "4" @default.
- NCIT_C1306 hasExactSynonym "2-amino-6-(benzyloxy)purine" @default.
- NCIT_C1306 hasExactSynonym "2-amino-6-(phenylmethoxy)-9h-purine" @default.
- NCIT_C1306 hasExactSynonym "6-O-BENZYLGUANINE" @default.
- NCIT_C1306 hasExactSynonym "6-O-Benzylguanine" @default.
- NCIT_C1306 hasExactSynonym "O(6)-Benzylguanine" @default.
- NCIT_C1306 hasExactSynonym "O(6)-benzylguanine" @default.
- NCIT_C1306 hasExactSynonym "O-6-Benzylguanine" @default.
- NCIT_C1306 hasExactSynonym "O6-BG" @default.
- NCIT_C1306 hasExactSynonym "O6-Benzylguanine" @default.
- NCIT_C1306 inSubset NCIT_C116977 @default.
- NCIT_C1306 inSubset NCIT_C116978 @default.
- NCIT_C1306 inSubset NCIT_C128784 @default.
- NCIT_C1306 inSubset NCIT_C157711 @default.
- NCIT_C1306 inSubset NCIT_C157712 @default.
- NCIT_C1306 inSubset NCIT_C176424 @default.
- NCIT_C1306 inSubset NCIT_C177537 @default.
- NCIT_C1306 inSubset NCIT_C63923 @default.
- NCIT_C1306 type Class @default.
- NCIT_C1306 isDefinedBy ncit.owl @default.
- NCIT_C1306 label "O6-Benzylguanine" @default.
- NCIT_C1306 subClassOf NCIT_C1306 @default.
- NCIT_C1306 subClassOf NCIT_C1908 @default.
- NCIT_C1306 subClassOf NCIT_C1909 @default.
- NCIT_C1306 subClassOf NCIT_C2134 @default.
- NCIT_C1306 subClassOf NCIT_C471 @default.
- NCIT_C1306 equivalentClass Ba43b58590e931a116c5eb32415ea8b98 @default.
- NCIT_C1306 equivalentClass Bbbb8ae3afc3c66ca3d4d6cebf7ae5974 @default.