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- NCIT_C1318 IAO_0000115 "The carbonate salt of lithium, a soft alkali metal, with antimanic and hematopoietic activities. Lithium interferes with transmembrane sodium exchange in nerve cells by affecting sodium, potassium-stimulated adenosine triphosphatase (Na+, K+-ATPase); alters the release of neurotransmitters; affects cyclic adenosine monophosphate (cAMP) concentrations; and blocks inositol metabolism resulting in depletion of cellular inositol and inhibition of phospholipase C-mediated signal transduction. The exact mechanism through which lithium exerts its mood-stabilizing effect has not been established. In addition, lithium stimulates granulocytopoiesis and appears to increase the level of pluripotent hematopoietic stem cells by stimulating the release of hematopoietic cytokines and/or directly acting on hematopoietic stem cells." @default.
- NCIT_C1318 NCIT_NHC0 "C1318" @default.
- NCIT_C1318 NCIT_P106 "Inorganic Chemical" @default.
- NCIT_C1318 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1318 NCIT_P107 "Lithium Carbonate" @default.
- NCIT_C1318 NCIT_P108 "Lithium Carbonate" @default.
- NCIT_C1318 NCIT_P175 "16895" @default.
- NCIT_C1318 NCIT_P207 "C0085217" @default.
- NCIT_C1318 NCIT_P210 "554-13-2" @default.
- NCIT_C1318 NCIT_P319 "2BMD2GNA4V" @default.
- NCIT_C1318 NCIT_P322 "CTRP" @default.
- NCIT_C1318 NCIT_P322 "FDA" @default.
- NCIT_C1318 NCIT_P329 "39491" @default.
- NCIT_C1318 NCIT_P330 "39491" @default.
- NCIT_C1318 NCIT_P350 "CO3.2Li" @default.
- NCIT_C1318 NCIT_P366 "Lithium_Carbonate" @default.
- NCIT_C1318 NCIT_P368 "CHEBI:6504" @default.
- NCIT_C1318 NCIT_P399 "39491" @default.
- NCIT_C1318 normalizedInformationContent "100" @default.
- NCIT_C1318 referenceCount "1" @default.
- NCIT_C1318 hasExactSynonym "Escalith" @default.
- NCIT_C1318 hasExactSynonym "Eskalith" @default.
- NCIT_C1318 hasExactSynonym "LITHIUM CARBONATE" @default.
- NCIT_C1318 hasExactSynonym "Lithane" @default.
- NCIT_C1318 hasExactSynonym "Lithium Carbonate" @default.
- NCIT_C1318 hasExactSynonym "Lithium carbonate" @default.
- NCIT_C1318 hasExactSynonym "Lithium" @default.
- NCIT_C1318 hasExactSynonym "Lithobid" @default.
- NCIT_C1318 hasExactSynonym "Lithonate" @default.
- NCIT_C1318 hasExactSynonym "Lithotabs" @default.
- NCIT_C1318 inSubset NCIT_C116977 @default.
- NCIT_C1318 inSubset NCIT_C116978 @default.
- NCIT_C1318 inSubset NCIT_C176424 @default.
- NCIT_C1318 inSubset NCIT_C63923 @default.
- NCIT_C1318 type Class @default.
- NCIT_C1318 isDefinedBy ncit.owl @default.
- NCIT_C1318 label "Lithium Carbonate" @default.
- NCIT_C1318 subClassOf NCIT_C1318 @default.
- NCIT_C1318 subClassOf NCIT_C1908 @default.
- NCIT_C1318 subClassOf NCIT_C1909 @default.
- NCIT_C1318 subClassOf NCIT_C29710 @default.
- NCIT_C1318 subClassOf NCIT_C78272 @default.