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- NCIT_C1374 IAO_0000115 "A synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH) with antineoplastic activity. Goserelin binds to and activates pituitary gonadotropin releasing hormone (GnRH) receptors. Prolonged administration of goserelin inhibits the secretion of pituitary gonadotropin, thereby decreasing levels of testosterone (in males) and estradiol (in females). Administration of this agent in a depot formulation may result in the regression of sex hormone-sensitive tumors and a reduction in sex organ size and function. (NCI04)" @default.
- NCIT_C1374 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1374 NCIT_A5 NCIT_C1417 @default.
- NCIT_C1374 NCIT_A7 NCIT_C38910 @default.
- NCIT_C1374 NCIT_NHC0 "C1374" @default.
- NCIT_C1374 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C1374 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1374 NCIT_P107 "Goserelin" @default.
- NCIT_C1374 NCIT_P108 "Goserelin" @default.
- NCIT_C1374 NCIT_P207 "C0120107" @default.
- NCIT_C1374 NCIT_P210 "65807-02-5" @default.
- NCIT_C1374 NCIT_P302 "Breast cancer; Endometrial-thinning; Endometriosis; In vitro fertilization; Prostate cancer" @default.
- NCIT_C1374 NCIT_P319 "0F65R8P09N" @default.
- NCIT_C1374 NCIT_P322 "CTRP" @default.
- NCIT_C1374 NCIT_P322 "FDA" @default.
- NCIT_C1374 NCIT_P322 "GDC" @default.
- NCIT_C1374 NCIT_P322 "OORO" @default.
- NCIT_C1374 NCIT_P325 "A drug that belongs to the family of drugs called gonadotropin-releasing hormone analogues. Goserelin is used to block hormone production in the ovaries or testicles." @default.
- NCIT_C1374 NCIT_P350 "C59H84N18O14" @default.
- NCIT_C1374 NCIT_P366 "Goserelin" @default.
- NCIT_C1374 NCIT_P375 "Goserelin" @default.
- NCIT_C1374 normalizedInformationContent "82.080392758357064" @default.
- NCIT_C1374 referenceCount "15" @default.
- NCIT_C1374 hasExactSynonym "6-[O-(1,1-Dimethylethyl)-D-serine]-10-deglycinamide Luteinizing Hormone-Releasing Factor (Pig) 2-(aminocarbonyl)hydrazide" @default.
- NCIT_C1374 hasExactSynonym "GOSERELIN" @default.
- NCIT_C1374 hasExactSynonym "Goserelin" @default.
- NCIT_C1374 hasExactSynonym "ICI-118630" @default.
- NCIT_C1374 hasExactSynonym "goserelin" @default.
- NCIT_C1374 inSubset NCIT_C116977 @default.
- NCIT_C1374 inSubset NCIT_C116978 @default.
- NCIT_C1374 inSubset NCIT_C128784 @default.
- NCIT_C1374 inSubset NCIT_C157711 @default.
- NCIT_C1374 inSubset NCIT_C157712 @default.
- NCIT_C1374 inSubset NCIT_C177537 @default.
- NCIT_C1374 inSubset NCIT_C192234 @default.
- NCIT_C1374 inSubset NCIT_C63923 @default.
- NCIT_C1374 type Class @default.
- NCIT_C1374 isDefinedBy ncit.owl @default.
- NCIT_C1374 label "Goserelin" @default.
- NCIT_C1374 subClassOf NCIT_C1374 @default.
- NCIT_C1374 subClassOf NCIT_C147908 @default.
- NCIT_C1374 subClassOf NCIT_C1908 @default.
- NCIT_C1374 subClassOf NCIT_C1909 @default.
- NCIT_C1374 subClassOf NCIT_C1910 @default.
- NCIT_C1374 subClassOf NCIT_C548 @default.