FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W137704210> ?p ?o ?g. }

• W137704210 endingPage "55" @default.
• W137704210 startingPage "1548" @default.
• W137704210 abstract "Recent data suggest that interferon-gamma release assays may have reduced sensitivity in children.To explore the cellular responses in children infected with tuberculosis (TB) to different mycobacterial antigens, including the peptides used in the QuantiFERON®-TB Gold In-Tube (QFT) assay.Cytokines were measured by multiplex analyte detection in supernatants after stimulation with peptides in QFT, purified protein derivative (PPD) and recombinant whole protein ESAT-6. Samples from 11 children with active TB, 46 healthy children with latent tuberculosis infection (LTBI), and 35 healthy non-infected children were analyzed.None of the cytokines examined in the QFT peptide stimulation assay distinguished between non-infected children and those aged <5 years with LTBI. Cytokines interleukin-2 and transforming growth factor-beta 1 (TGF-β1) were shown to distinguish between stages of Mycobacterium tuberculosis infection after blood was stimulated with the QFT peptides. All children had significantly higher Th 1 and 2 cytokine production against PPD than against the other antigens tested.Measuring specific cytokine patterns after stimulation with the QFT peptides may not increase sensitivity in diagnosing LTBI in children, but there may be future diagnostic value in determining the stage of infection. PPD-stimulated blood produced a robust and diverse cytokine response in young children, making it an interesting antigen for in vitro diagnostic studies." @default.
• W137704210 created "2016-06-24" @default.
• W137704210 creator A5057872440 @default.
• W137704210 creator A5073012394 @default.
• W137704210 creator A5087367977 @default.
• W137704210 date "2010-12-01" @default.
• W137704210 modified "2023-09-26" @default.
• W137704210 title "Cytokine responses to QuantiFERON® peptides, purified protein derivative and recombinant ESAT-6 in children with tuberculosis." @default.
• W137704210 cites W1661719389 @default.
• W137704210 cites W1741423199 @default.
• W137704210 cites W1913019479 @default.
• W137704210 cites W1982495124 @default.
• W137704210 cites W1985860622 @default.
• W137704210 cites W1989604051 @default.
• W137704210 cites W1991464170 @default.
• W137704210 cites W2001484027 @default.
• W137704210 cites W2004277240 @default.
• W137704210 cites W2006356263 @default.
• W137704210 cites W2035602962 @default.
• W137704210 cites W2051032566 @default.
• W137704210 cites W2059678333 @default.
• W137704210 cites W2065801924 @default.
• W137704210 cites W2067263905 @default.
• W137704210 cites W2067844252 @default.
• W137704210 cites W2096466498 @default.
• W137704210 cites W2097863119 @default.
• W137704210 cites W2105420101 @default.
• W137704210 cites W2110293179 @default.
• W137704210 cites W2119122291 @default.
• W137704210 cites W2120521419 @default.
• W137704210 cites W2124011507 @default.
• W137704210 cites W2128019577 @default.
• W137704210 cites W2129627612 @default.
• W137704210 cites W2132934821 @default.
• W137704210 cites W2141700270 @default.
• W137704210 cites W2149637134 @default.
• W137704210 cites W2149672664 @default.
• W137704210 cites W2154239844 @default.
• W137704210 cites W2156388410 @default.
• W137704210 cites W2156799706 @default.
• W137704210 cites W2161784221 @default.
• W137704210 cites W2162261192 @default.
• W137704210 cites W2169180677 @default.
• W137704210 cites W2172219815 @default.
• W137704210 cites W3080290749 @default.
• W137704210 cites W86750161 @default.
• W137704210 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21144239" @default.
• W137704210 hasPublicationYear "2010" @default.
• W137704210 type Work @default.
• W137704210 sameAs 137704210 @default.
• W137704210 citedByCount "6" @default.
• W137704210 countsByYear W1377042102012 @default.
• W137704210 countsByYear W1377042102013 @default.
• W137704210 countsByYear W1377042102014 @default.
• W137704210 countsByYear W1377042102015 @default.
• W137704210 countsByYear W1377042102016 @default.
• W137704210 countsByYear W1377042102019 @default.
• W137704210 crossrefType "journal-article" @default.
• W137704210 hasAuthorship W137704210A5057872440 @default.
• W137704210 hasAuthorship W137704210A5073012394 @default.
• W137704210 hasAuthorship W137704210A5087367977 @default.
• W137704210 hasConcept C142724271 @default.
• W137704210 hasConcept C153911025 @default.
• W137704210 hasConcept C203014093 @default.
• W137704210 hasConcept C2777975735 @default.
• W137704210 hasConcept C2778690821 @default.
• W137704210 hasConcept C2781069245 @default.
• W137704210 hasConcept C71924100 @default.
• W137704210 hasConcept C86803240 @default.
• W137704210 hasConceptScore W137704210C142724271 @default.
• W137704210 hasConceptScore W137704210C153911025 @default.
• W137704210 hasConceptScore W137704210C203014093 @default.
• W137704210 hasConceptScore W137704210C2777975735 @default.
• W137704210 hasConceptScore W137704210C2778690821 @default.
• W137704210 hasConceptScore W137704210C2781069245 @default.
• W137704210 hasConceptScore W137704210C71924100 @default.
• W137704210 hasConceptScore W137704210C86803240 @default.
• W137704210 hasIssue "12" @default.
• W137704210 hasLocation W1377042101 @default.
• W137704210 hasOpenAccess W137704210 @default.
• W137704210 hasPrimaryLocation W1377042101 @default.
• W137704210 hasRelatedWork W1847249683 @default.
• W137704210 hasRelatedWork W1970934635 @default.
• W137704210 hasRelatedWork W1973859465 @default.
• W137704210 hasRelatedWork W2004811983 @default.
• W137704210 hasRelatedWork W2010560075 @default.
• W137704210 hasRelatedWork W2015457648 @default.
• W137704210 hasRelatedWork W2028462978 @default.
• W137704210 hasRelatedWork W2031752265 @default.
• W137704210 hasRelatedWork W2039455162 @default.
• W137704210 hasRelatedWork W2039873011 @default.
• W137704210 hasRelatedWork W2043024272 @default.
• W137704210 hasRelatedWork W2061731104 @default.
• W137704210 hasRelatedWork W2093547008 @default.
• W137704210 hasRelatedWork W2121711622 @default.
• W137704210 hasRelatedWork W2124875533 @default.
• W137704210 hasRelatedWork W2125008418 @default.
• W137704210 hasRelatedWork W2127013418 @default.

• next