FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1507602988> ?p ?o ?g. }

• W1507602988 endingPage "1438" @default.
• W1507602988 startingPage "1431" @default.
• W1507602988 abstract "Basic properties of noradrenaline release were studied in primary cultures of thoracolumbar postganglionic sympathetic neurons taken from 1-3-day-old NMRI mice. After 7 days in vitro, the cultures were preincubated with [3H]noradrenaline and then superfused and stimulated electrically. Conventional trains of pulses (for example, 36 pulses at 3 Hz) as well as single pulses and brief high-frequency trains (for example, four pulses at 100 Hz) elicited a well-measurable overflow of tritium, which was abolished by 0.3 microM tetrodotoxin or omission of Ca2+, but not changed by 1 microM rauwolscine. In trains of one, two, four, six, eight, or 10 pulses at 3 Hz, the evoked overflow of tritium remained constant from pulse to pulse at 1.3 mM Ca2+, but declined slightly at 2.5 mM Ca2+. Tetraethylammonium at 10 mM selectively increased the overflow elicited by small pulse numbers and especially by a single pulse. In trains of 10 pulses delivered at 0.3, 1, 3, 10, 30, or 100 Hz, the evoked overflow of tritium increased from 0.3 to 30 Hz and then declined at 100 Hz. This relationship was particularly pronounced at low Ca2+ concentrations (for example, 0.3 mM). Tetraethylammonium at 10 mM selectively increased the overflow elicited by low frequencies of stimulation. It is concluded that primary cultures of mouse postganglionic sympathetic neurons can be used to investigate release of [3H]noradrenaline. The release is well measurable, even upon a single electrical pulse. It agrees with release in intact sympathetically innervated tissues in a number of fundamental properties, including the pulse number and frequency dependence. The preparation may be of special interest in conjunction with genetic manipulations in the donor animals." @default.
• W1507602988 created "2016-06-24" @default.
• W1507602988 creator A5007905634 @default.
• W1507602988 creator A5045144929 @default.
• W1507602988 creator A5049724951 @default.
• W1507602988 creator A5054977809 @default.
• W1507602988 creator A5056835151 @default.
• W1507602988 date "2002-01-17" @default.
• W1507602988 modified "2023-10-14" @default.
• W1507602988 title "Mouse Postganglionic Sympathetic Neurons" @default.
• W1507602988 cites W1488521817 @default.
• W1507602988 cites W1564218032 @default.
• W1507602988 cites W179498732 @default.
• W1507602988 cites W1971841262 @default.
• W1507602988 cites W1980044156 @default.
• W1507602988 cites W2002093874 @default.
• W1507602988 cites W2021506248 @default.
• W1507602988 cites W2033404256 @default.
• W1507602988 cites W2035267851 @default.
• W1507602988 cites W2041805712 @default.
• W1507602988 cites W2045332499 @default.
• W1507602988 cites W2049035392 @default.
• W1507602988 cites W2050221161 @default.
• W1507602988 cites W2053321947 @default.
• W1507602988 cites W2055204420 @default.
• W1507602988 cites W2060788994 @default.
• W1507602988 cites W2063937262 @default.
• W1507602988 cites W2069803172 @default.
• W1507602988 cites W2073634787 @default.
• W1507602988 cites W2088480227 @default.
• W1507602988 cites W2091909782 @default.
• W1507602988 cites W2095312523 @default.
• W1507602988 cites W2111982992 @default.
• W1507602988 cites W2139831835 @default.
• W1507602988 cites W2163238968 @default.
• W1507602988 cites W337114244 @default.
• W1507602988 cites W72363943 @default.
• W1507602988 doi "https://doi.org/10.1046/j.1471-4159.1999.0731431.x" @default.
• W1507602988 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10501186" @default.
• W1507602988 hasPublicationYear "2002" @default.
• W1507602988 type Work @default.
• W1507602988 sameAs 1507602988 @default.
• W1507602988 citedByCount "11" @default.
• W1507602988 countsByYear W15076029882013 @default.
• W1507602988 crossrefType "journal-article" @default.
• W1507602988 hasAuthorship W1507602988A5007905634 @default.
• W1507602988 hasAuthorship W1507602988A5045144929 @default.
• W1507602988 hasAuthorship W1507602988A5049724951 @default.
• W1507602988 hasAuthorship W1507602988A5054977809 @default.
• W1507602988 hasAuthorship W1507602988A5056835151 @default.
• W1507602988 hasConcept C120665830 @default.
• W1507602988 hasConcept C121332964 @default.
• W1507602988 hasConcept C12554922 @default.
• W1507602988 hasConcept C126322002 @default.
• W1507602988 hasConcept C134018914 @default.
• W1507602988 hasConcept C170493617 @default.
• W1507602988 hasConcept C178790620 @default.
• W1507602988 hasConcept C185544564 @default.
• W1507602988 hasConcept C185592680 @default.
• W1507602988 hasConcept C24998067 @default.
• W1507602988 hasConcept C2776504411 @default.
• W1507602988 hasConcept C2776741303 @default.
• W1507602988 hasConcept C2776885963 @default.
• W1507602988 hasConcept C2780167933 @default.
• W1507602988 hasConcept C2780648677 @default.
• W1507602988 hasConcept C2781295685 @default.
• W1507602988 hasConcept C517785266 @default.
• W1507602988 hasConcept C55493867 @default.
• W1507602988 hasConcept C62538594 @default.
• W1507602988 hasConcept C71924100 @default.
• W1507602988 hasConcept C86803240 @default.
• W1507602988 hasConcept C94915269 @default.
• W1507602988 hasConceptScore W1507602988C120665830 @default.
• W1507602988 hasConceptScore W1507602988C121332964 @default.
• W1507602988 hasConceptScore W1507602988C12554922 @default.
• W1507602988 hasConceptScore W1507602988C126322002 @default.
• W1507602988 hasConceptScore W1507602988C134018914 @default.
• W1507602988 hasConceptScore W1507602988C170493617 @default.
• W1507602988 hasConceptScore W1507602988C178790620 @default.
• W1507602988 hasConceptScore W1507602988C185544564 @default.
• W1507602988 hasConceptScore W1507602988C185592680 @default.
• W1507602988 hasConceptScore W1507602988C24998067 @default.
• W1507602988 hasConceptScore W1507602988C2776504411 @default.
• W1507602988 hasConceptScore W1507602988C2776741303 @default.
• W1507602988 hasConceptScore W1507602988C2776885963 @default.
• W1507602988 hasConceptScore W1507602988C2780167933 @default.
• W1507602988 hasConceptScore W1507602988C2780648677 @default.
• W1507602988 hasConceptScore W1507602988C2781295685 @default.
• W1507602988 hasConceptScore W1507602988C517785266 @default.
• W1507602988 hasConceptScore W1507602988C55493867 @default.
• W1507602988 hasConceptScore W1507602988C62538594 @default.
• W1507602988 hasConceptScore W1507602988C71924100 @default.
• W1507602988 hasConceptScore W1507602988C86803240 @default.
• W1507602988 hasConceptScore W1507602988C94915269 @default.
• W1507602988 hasIssue "4" @default.
• W1507602988 hasLocation W15076029881 @default.
• W1507602988 hasLocation W15076029882 @default.
• W1507602988 hasOpenAccess W1507602988 @default.

• next