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- W1905727768 abstract "Hepatitis C virus (HCV) is an enveloped, positive-strand RNA virus of the family Flaviviridae that primarily infects hepatocytes, causing acute and chronic liver disease. HCV is also associated with a variety of extrahepatic symptoms including central nervous system (CNS) abnormalities, cognitive dysfunction, fatigue and depression. These symptoms do not correlate with the severity of liver disease and are independent of hepatic encephalopathy. HCV RNA has been associated with CNS tissue, and reports of viral sequence diversity between brain and liver tissue suggest independent viral evolution in the CNS and liver. This review will explore the data supporting HCV infection of the CNS and how this fits into our current understanding of HCV pathogenesis." @default.
- W1905727768 created "2016-06-24" @default.
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- W1905727768 date "2012-04-13" @default.
- W1905727768 modified "2023-10-14" @default.
- W1905727768 title "Hepatitis C virus and the brain" @default.
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- W1905727768 doi "https://doi.org/10.1111/j.1365-2893.2012.01591.x" @default.
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