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- W1953952736 endingPage "194" @default.
- W1953952736 startingPage "171" @default.
- W1953952736 abstract "The increasing prevalence of allergy in affluent countries may be caused by the reduced intensity and diversity of microbial stimulation, resulting in abnormal postnatal immune maturation. Allergy development is associated with differences in gut microbiota composition and diversity during the first months of life. Early establishment of a diverse gut microbiota may be more important than the distribution of specific microbial species in shaping normal immune maturation. The maternal microbial environment during pregnancy, as well as the pioneer microbiome provided to the child during vaginal delivery, may also crucially influence immune programming. Combined prenatal and postnatal supplementation seems to be crucial for the preventive effect of probiotics on infant eczema. Probiotic interventions have so far failed to prevent asthma, however. Further studies on the appropriate timing of interventions and the complex interactions between the infant immune system and the microbiome are required to identify preventive strategies to combat the asthma and allergy epidemic." @default.
- W1953952736 created "2016-06-24" @default.
- W1953952736 creator A5011411105 @default.
- W1953952736 creator A5091351540 @default.
- W1953952736 date "2016-01-01" @default.
- W1953952736 modified "2023-10-01" @default.
- W1953952736 title "Microbiome and the Effect on Immune Response" @default.
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