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- W1964570745 abstract "Abstract. Autoimmune polyendocrine syndromes type 1 and 2 (APS‐1 and APS‐2) are diverse in regards to their component diseases and immunologic features of pathogenesis. Animal models and human studies highlight the importance of alleles of HLA (human leukocyte antigen)‐like molecules determining tissue specific targeting that with the loss of tolerance leads to organ specific autoimmunity. Knowledge of the syndromes and component diseases allows clinicians to recognize and prevent illness prior to morbidity. With the current understanding of the syndromes, a paradigm for diagnosis, screening and treatment can be established. Once genetically susceptible individuals are identified screening for autoantibodies can be performed. Amongst autoantibody positive individuals, monitoring for physiologic decompensation, with a goal of treating prior to morbidity and in some cases mortality, follows. With continued basic and clinical research, therapies aimed at treating the underlying autoimmunity and disease prevention should become possible." @default.
- W1964570745 created "2016-06-24" @default.
- W1964570745 creator A5035095598 @default.
- W1964570745 creator A5038398583 @default.
- W1964570745 date "2009-04-06" @default.
- W1964570745 modified "2023-10-18" @default.
- W1964570745 title "Autoimmune polyendocrine syndrome type 1 (APS-1) as a model for understanding autoimmune polyendocrine syndrome type 2 (APS-2)" @default.
- W1964570745 cites W1521451515 @default.
- W1964570745 cites W1545313141 @default.
- W1964570745 cites W1630776565 @default.
- W1964570745 cites W1666984035 @default.
- W1964570745 cites W1980888826 @default.
- W1964570745 cites W1988916167 @default.
- W1964570745 cites W1991294321 @default.
- W1964570745 cites W1993312496 @default.
- W1964570745 cites W1996008085 @default.
- W1964570745 cites W2008717439 @default.
- W1964570745 cites W2009596665 @default.
- W1964570745 cites W2012962101 @default.
- W1964570745 cites W2014077667 @default.
- W1964570745 cites W2017447254 @default.
- W1964570745 cites W2019847534 @default.
- W1964570745 cites W2019972832 @default.
- W1964570745 cites W2026468137 @default.
- W1964570745 cites W2027773858 @default.
- W1964570745 cites W2031819338 @default.
- W1964570745 cites W2034937079 @default.
- W1964570745 cites W2038142359 @default.
- W1964570745 cites W2048548715 @default.
- W1964570745 cites W2049654479 @default.
- W1964570745 cites W2050040308 @default.
- W1964570745 cites W2050538525 @default.
- W1964570745 cites W2058368144 @default.
- W1964570745 cites W2059758349 @default.
- W1964570745 cites W2060195896 @default.
- W1964570745 cites W2060312395 @default.
- W1964570745 cites W2062517948 @default.
- W1964570745 cites W2074463323 @default.
- W1964570745 cites W2078509644 @default.
- W1964570745 cites W2079212525 @default.
- W1964570745 cites W2083737302 @default.
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- W1964570745 cites W2135200130 @default.
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- W1964570745 cites W2153850116 @default.
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- W1964570745 cites W2154817327 @default.
- W1964570745 cites W2156959273 @default.
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- W1964570745 doi "https://doi.org/10.1111/j.1365-2796.2009.02091.x" @default.
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