FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966530668> ?p ?o ?g. }

• W1966530668 endingPage "89" @default.
• W1966530668 startingPage "76" @default.
• W1966530668 abstract "A circumferential marginal zone (CMZ) of retinal progenitors has been identified in most vertebrate classes, with the exception of mammals. Little is known about the formation of the CMZ during late stages of embryonic retinal histogenesis. Thus, the purpose of this study was to characterize the formation and patterning of the CMZ in the embryonic chicken retina. We identified progenitors by assaying for the expression of proliferating cell nuclear antigen (PCNA), N-cadherin and the nestin-related filament transitin, and newly generated cells by using BrdU-birthdating. We found that there is a gradual spatial restriction of progenitors into a discreet CMZ during late stages of embryonic development between E16 and hatching, at about E21. In addition, we found that retinal neurons remain immature for prolonged periods of time in far peripheral regions of the retina. Early markers of neuronal differentiation (such as HuC/D, calretinin and visinin) are expressed by neurons that are found directly adjacent to the CMZ. By contrast, genes (protein kinase C, calbindin, red/green opsin) that are expressed with a delay (7–10 days) after terminal mitosis in the central retina are not expressed until as many as 30 days after terminal mitosis in the far peripheral retina. We conclude that the neurons that are generated by late-stage CMZ progenitors differentiate much more slowly than neurons generated during early stages of retinal development. We propose that the microenvironment within the far peripheral retina at late stages of development permits the maintenance of a zone of progenitors and slows the differentiation of neurons." @default.
• W1966530668 created "2016-06-24" @default.
• W1966530668 creator A5037828663 @default.
• W1966530668 creator A5063139808 @default.
• W1966530668 creator A5091788827 @default.
• W1966530668 date "2008-02-01" @default.
• W1966530668 modified "2023-09-26" @default.
• W1966530668 title "Patterning of the circumferential marginal zone of progenitors in the chicken retina" @default.
• W1966530668 cites W1942735643 @default.
• W1966530668 cites W1964270095 @default.
• W1966530668 cites W1968131623 @default.
• W1966530668 cites W1972262173 @default.
• W1966530668 cites W1975480238 @default.
• W1966530668 cites W1986727202 @default.
• W1966530668 cites W1993000387 @default.
• W1966530668 cites W1997572202 @default.
• W1966530668 cites W1999536218 @default.
• W1966530668 cites W2008277743 @default.
• W1966530668 cites W2017771872 @default.
• W1966530668 cites W2020420028 @default.
• W1966530668 cites W2030569690 @default.
• W1966530668 cites W2031927234 @default.
• W1966530668 cites W2032274661 @default.
• W1966530668 cites W2037041480 @default.
• W1966530668 cites W2042896866 @default.
• W1966530668 cites W2047044177 @default.
• W1966530668 cites W2049654456 @default.
• W1966530668 cites W2057202628 @default.
• W1966530668 cites W2057281544 @default.
• W1966530668 cites W2061033163 @default.
• W1966530668 cites W2067114202 @default.
• W1966530668 cites W2067468939 @default.
• W1966530668 cites W2077428235 @default.
• W1966530668 cites W2084582407 @default.
• W1966530668 cites W2084644999 @default.
• W1966530668 cites W2085924238 @default.
• W1966530668 cites W2086129220 @default.
• W1966530668 cites W2086213962 @default.
• W1966530668 cites W2099460012 @default.
• W1966530668 cites W2100264282 @default.
• W1966530668 cites W2102567777 @default.
• W1966530668 cites W2102812687 @default.
• W1966530668 cites W2104894923 @default.
• W1966530668 cites W2109876648 @default.
• W1966530668 cites W2109907626 @default.
• W1966530668 cites W2115612876 @default.
• W1966530668 cites W2131416478 @default.
• W1966530668 cites W2131983859 @default.
• W1966530668 cites W2132862664 @default.
• W1966530668 cites W2143550055 @default.
• W1966530668 cites W2149725942 @default.
• W1966530668 cites W2153073720 @default.
• W1966530668 cites W2160391559 @default.
• W1966530668 cites W2162463187 @default.
• W1966530668 cites W2169344378 @default.
• W1966530668 cites W2214673052 @default.
• W1966530668 cites W4251966608 @default.
• W1966530668 doi "https://doi.org/10.1016/j.brainres.2007.01.105" @default.
• W1966530668 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2775427" @default.
• W1966530668 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17320838" @default.
• W1966530668 hasPublicationYear "2008" @default.
• W1966530668 type Work @default.
• W1966530668 sameAs 1966530668 @default.
• W1966530668 citedByCount "36" @default.
• W1966530668 countsByYear W19665306682012 @default.
• W1966530668 countsByYear W19665306682013 @default.
• W1966530668 countsByYear W19665306682014 @default.
• W1966530668 countsByYear W19665306682015 @default.
• W1966530668 countsByYear W19665306682016 @default.
• W1966530668 countsByYear W19665306682017 @default.
• W1966530668 countsByYear W19665306682020 @default.
• W1966530668 countsByYear W19665306682021 @default.
• W1966530668 countsByYear W19665306682022 @default.
• W1966530668 countsByYear W19665306682023 @default.
• W1966530668 crossrefType "journal-article" @default.
• W1966530668 hasAuthorship W1966530668A5037828663 @default.
• W1966530668 hasAuthorship W1966530668A5063139808 @default.
• W1966530668 hasAuthorship W1966530668A5091788827 @default.
• W1966530668 hasBestOaLocation W19665306682 @default.
• W1966530668 hasConcept C104317684 @default.
• W1966530668 hasConcept C105702510 @default.
• W1966530668 hasConcept C145103041 @default.
• W1966530668 hasConcept C159654299 @default.
• W1966530668 hasConcept C169760540 @default.
• W1966530668 hasConcept C201750760 @default.
• W1966530668 hasConcept C203014093 @default.
• W1966530668 hasConcept C204232928 @default.
• W1966530668 hasConcept C2777093970 @default.
• W1966530668 hasConcept C2778453870 @default.
• W1966530668 hasConcept C2779921676 @default.
• W1966530668 hasConcept C2780827179 @default.
• W1966530668 hasConcept C2781404787 @default.
• W1966530668 hasConcept C28328180 @default.
• W1966530668 hasConcept C54355233 @default.
• W1966530668 hasConcept C55493867 @default.
• W1966530668 hasConcept C86803240 @default.
• W1966530668 hasConcept C95444343 @default.
• W1966530668 hasConceptScore W1966530668C104317684 @default.

• next