Matches in SemOpenAlex for { <https://semopenalex.org/work/W1967874296> ?p ?o ?g. }
- W1967874296 endingPage "3736" @default.
- W1967874296 startingPage "3731" @default.
- W1967874296 abstract "Hepatitis B (HB) vaccine induces protective levels of antibody response (anti-HBs ≥ 10 mIU/mL) in 90–99% of vaccinees. The levels of anti-HBs antibody decline after vaccination. The aim of this study was to evaluate the persistence of anti-HBs antibodies and immunologic memory in healthy adults at 20 years after primary vaccination with recombinant HB vaccine. Blood samples were collected from 300 adults at 20 years after primary HB vaccination and their sera were tested for anti-HBs antibody by ELISA technique. A single booster dose of HB vaccine was administered to a total of 138 subjects, whose anti-HBs antibody titer was <10 mIU/mL. The sera of subjects were re-tested for the anti-HBs antibody levels at 4 weeks after booster vaccination. At 20 years after primary vaccination 37.0% of participants had protective levels of antibody with geometric mean titer (GMT) of 55.44 ± 77.01 mIU/mL. After booster vaccination, 97.1% of vaccinees developed protective levels of antibody and the GMT rose from 2.35 ± 6.49 mIU/mL to 176.28 ± 161.78 mIU/mL. 125/138 (90.6%) of re-vaccinated subjects also showed an anamnestic response to booster vaccination. At 20 years after primary vaccination with HB vaccine, low proportion of the subjects had protective levels of antibody. However, the majority of the re-vaccinated subjects developed protective levels of anti-HBs and showed an anamnestic response after booster vaccination. Additional follow-up studies are necessary to determine the duration of immunological memory." @default.
- W1967874296 created "2016-06-24" @default.
- W1967874296 creator A5006778805 @default.
- W1967874296 creator A5009540768 @default.
- W1967874296 creator A5013657282 @default.
- W1967874296 creator A5021724355 @default.
- W1967874296 creator A5030882337 @default.
- W1967874296 creator A5049462917 @default.
- W1967874296 creator A5072292697 @default.
- W1967874296 creator A5079032912 @default.
- W1967874296 creator A5085113824 @default.
- W1967874296 date "2014-11-01" @default.
- W1967874296 modified "2023-10-01" @default.
- W1967874296 title "The persistence of anti-HBs antibody and anamnestic response 20 years after primary vaccination with recombinant hepatitis B vaccine at infancy" @default.
- W1967874296 cites W168281371 @default.
- W1967874296 cites W1975436361 @default.
- W1967874296 cites W1978629773 @default.
- W1967874296 cites W1981896569 @default.
- W1967874296 cites W1983001695 @default.
- W1967874296 cites W1983225666 @default.
- W1967874296 cites W2004594897 @default.
- W1967874296 cites W2006229170 @default.
- W1967874296 cites W2006482447 @default.
- W1967874296 cites W2009120131 @default.
- W1967874296 cites W2010057931 @default.
- W1967874296 cites W2017042129 @default.
- W1967874296 cites W2023190977 @default.
- W1967874296 cites W2031907120 @default.
- W1967874296 cites W2035729482 @default.
- W1967874296 cites W2037099233 @default.
- W1967874296 cites W2040581859 @default.
- W1967874296 cites W2064768091 @default.
- W1967874296 cites W2065487163 @default.
- W1967874296 cites W2067109440 @default.
- W1967874296 cites W2068204482 @default.
- W1967874296 cites W2070287117 @default.
- W1967874296 cites W2079840144 @default.
- W1967874296 cites W2115168527 @default.
- W1967874296 cites W2132461311 @default.
- W1967874296 cites W2132876251 @default.
- W1967874296 cites W2151647451 @default.
- W1967874296 cites W2160677902 @default.
- W1967874296 cites W2163274841 @default.
- W1967874296 cites W2170771423 @default.
- W1967874296 cites W2555731396 @default.
- W1967874296 cites W2991904559 @default.
- W1967874296 cites W4210957534 @default.
- W1967874296 cites W4292216730 @default.
- W1967874296 doi "https://doi.org/10.4161/hv.34393" @default.
- W1967874296 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4514033" @default.
- W1967874296 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25483689" @default.
- W1967874296 hasPublicationYear "2014" @default.
- W1967874296 type Work @default.
- W1967874296 sameAs 1967874296 @default.
- W1967874296 citedByCount "42" @default.
- W1967874296 countsByYear W19678742962016 @default.
- W1967874296 countsByYear W19678742962017 @default.
- W1967874296 countsByYear W19678742962018 @default.
- W1967874296 countsByYear W19678742962019 @default.
- W1967874296 countsByYear W19678742962020 @default.
- W1967874296 countsByYear W19678742962021 @default.
- W1967874296 countsByYear W19678742962022 @default.
- W1967874296 countsByYear W19678742962023 @default.
- W1967874296 crossrefType "journal-article" @default.
- W1967874296 hasAuthorship W1967874296A5006778805 @default.
- W1967874296 hasAuthorship W1967874296A5009540768 @default.
- W1967874296 hasAuthorship W1967874296A5013657282 @default.
- W1967874296 hasAuthorship W1967874296A5021724355 @default.
- W1967874296 hasAuthorship W1967874296A5030882337 @default.
- W1967874296 hasAuthorship W1967874296A5049462917 @default.
- W1967874296 hasAuthorship W1967874296A5072292697 @default.
- W1967874296 hasAuthorship W1967874296A5079032912 @default.
- W1967874296 hasAuthorship W1967874296A5085113824 @default.
- W1967874296 hasBestOaLocation W19678742961 @default.
- W1967874296 hasConcept C12590561 @default.
- W1967874296 hasConcept C159047783 @default.
- W1967874296 hasConcept C159654299 @default.
- W1967874296 hasConcept C203014093 @default.
- W1967874296 hasConcept C22070199 @default.
- W1967874296 hasConcept C22889606 @default.
- W1967874296 hasConcept C2777382497 @default.
- W1967874296 hasConcept C32611913 @default.
- W1967874296 hasConcept C71924100 @default.
- W1967874296 hasConceptScore W1967874296C12590561 @default.
- W1967874296 hasConceptScore W1967874296C159047783 @default.
- W1967874296 hasConceptScore W1967874296C159654299 @default.
- W1967874296 hasConceptScore W1967874296C203014093 @default.
- W1967874296 hasConceptScore W1967874296C22070199 @default.
- W1967874296 hasConceptScore W1967874296C22889606 @default.
- W1967874296 hasConceptScore W1967874296C2777382497 @default.
- W1967874296 hasConceptScore W1967874296C32611913 @default.
- W1967874296 hasConceptScore W1967874296C71924100 @default.
- W1967874296 hasIssue "12" @default.
- W1967874296 hasLocation W19678742961 @default.
- W1967874296 hasLocation W19678742962 @default.
- W1967874296 hasLocation W19678742963 @default.
- W1967874296 hasLocation W19678742964 @default.
- W1967874296 hasOpenAccess W1967874296 @default.