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• W1969134779 abstract "Polar polyoxyethylene-polyoxypropylene (POEPOP) resin was derivatised with a 4-hydroxymethyl phenoxy linker and used as a solid support for lanthanide triflate catalysed Mukaiyama type solid phase aldol reactions. The conditions were optimised using resin bound 4-alkoxybenzaldehyde and it was shown that use of an aqueous solvent was crucial. Also, the reactions were performed with an N-terminal peptide aldehyde substrate in very high yields. POEPOP resins prepared with different monomer chain lengths and commercially available PEG-grafted NovaSyn TG resin were compared in the reactions." @default.
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• W1969134779 date "2000-01-01" @default.
• W1969134779 modified "2023-10-18" @default.
• W1969134779 title "Towards peptide isostere libraries: aqueous aldol reactions on hydrophilic solid supports" @default.
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• W1969134779 doi "https://doi.org/10.1039/a909246c" @default.
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