FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1970742783> ?p ?o ?g. }

• W1970742783 endingPage "S16" @default.
• W1970742783 startingPage "S9" @default.
• W1970742783 abstract "Diversity of microbicide delivery systems is essential for future success in the prevention and treatment of HIV in order to account for the varied populations of women all over the world that may benefit from use of these products. Recently, a novel dosage form for intravaginal drug delivery has been developed using drug-eluting fibers fabricated by electrospinning. There is a strong rationale to support the idea that drug-eluting fibers can be designed to realize multiple design constraints in a single product for topical HIV prevention: fibers are able to deliver a wide range of agents, incorporate multiple agents via composites, and facilitate controlled release over relevant time frames for pericoital and sustained (coitally-independent) use. It is also technologically feasible to scale-up production of fiber-based microbicides. Electrospun fibers may allow for prioritization of physical attributes that affect user perceptions without compromising biological efficacy. Challenges with using fibers as a microbicide include issues related to vehicle deployment, spreading and retention in the vaginal vault. In addition, studies will need to address the interaction of the fibers with the mucosal environment, including unknown safety and toxicity. Sustained release fiber microbicides capable of delivering multiple antiretroviral drugs while simultaneously exhibiting tunable degradation or dissolution of the fibers is also a challenge. However, electrospun fibers are a promising new platform for vaginal delivery of anti-HIV agents and future research will inform their place in the field. This article is based on a presentation at the “Product Development Workshop 2013: HIV and Multipurpose Prevention Technologies”, held in Arlington, Virginia on February 20–21, 2013. It forms part of a special supplement to Antiviral Research." @default.
• W1970742783 created "2016-06-24" @default.
• W1970742783 creator A5046773398 @default.
• W1970742783 creator A5063242540 @default.
• W1970742783 creator A5069057400 @default.
• W1970742783 creator A5079681801 @default.
• W1970742783 date "2013-12-01" @default.
• W1970742783 modified "2023-09-28" @default.
• W1970742783 title "Electrospun fibers for vaginal anti-HIV drug delivery" @default.
• W1970742783 cites W1520349470 @default.
• W1970742783 cites W1964477207 @default.
• W1970742783 cites W1964663356 @default.
• W1970742783 cites W1965750199 @default.
• W1970742783 cites W1979268079 @default.
• W1970742783 cites W1983067875 @default.
• W1970742783 cites W1985480688 @default.
• W1970742783 cites W1993905498 @default.
• W1970742783 cites W1997552417 @default.
• W1970742783 cites W2001901378 @default.
• W1970742783 cites W2002798467 @default.
• W1970742783 cites W2002981939 @default.
• W1970742783 cites W2003299916 @default.
• W1970742783 cites W2004272248 @default.
• W1970742783 cites W2006516628 @default.
• W1970742783 cites W2013796894 @default.
• W1970742783 cites W2017304504 @default.
• W1970742783 cites W2017964313 @default.
• W1970742783 cites W2020358670 @default.
• W1970742783 cites W2026192690 @default.
• W1970742783 cites W2044288894 @default.
• W1970742783 cites W2049282944 @default.
• W1970742783 cites W2060062181 @default.
• W1970742783 cites W2065009153 @default.
• W1970742783 cites W2065420625 @default.
• W1970742783 cites W2066980092 @default.
• W1970742783 cites W2071526286 @default.
• W1970742783 cites W2073136208 @default.
• W1970742783 cites W2075242633 @default.
• W1970742783 cites W2077287304 @default.
• W1970742783 cites W2078384071 @default.
• W1970742783 cites W2086483409 @default.
• W1970742783 cites W2090227057 @default.
• W1970742783 cites W2092140089 @default.
• W1970742783 cites W2093115787 @default.
• W1970742783 cites W209314204 @default.
• W1970742783 cites W2103924242 @default.
• W1970742783 cites W2110789325 @default.
• W1970742783 cites W2111634545 @default.
• W1970742783 cites W2124860488 @default.
• W1970742783 cites W2146634980 @default.
• W1970742783 cites W2149765887 @default.
• W1970742783 cites W2160064249 @default.
• W1970742783 cites W2160803146 @default.
• W1970742783 cites W2167993308 @default.
• W1970742783 cites W2179545372 @default.
• W1970742783 doi "https://doi.org/10.1016/j.antiviral.2013.09.022" @default.
• W1970742783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24188701" @default.
• W1970742783 hasPublicationYear "2013" @default.
• W1970742783 type Work @default.
• W1970742783 sameAs 1970742783 @default.
• W1970742783 citedByCount "86" @default.
• W1970742783 countsByYear W19707427832013 @default.
• W1970742783 countsByYear W19707427832014 @default.
• W1970742783 countsByYear W19707427832015 @default.
• W1970742783 countsByYear W19707427832016 @default.
• W1970742783 countsByYear W19707427832017 @default.
• W1970742783 countsByYear W19707427832018 @default.
• W1970742783 countsByYear W19707427832019 @default.
• W1970742783 countsByYear W19707427832020 @default.
• W1970742783 countsByYear W19707427832021 @default.
• W1970742783 countsByYear W19707427832022 @default.
• W1970742783 countsByYear W19707427832023 @default.
• W1970742783 crossrefType "journal-article" @default.
• W1970742783 hasAuthorship W1970742783A5046773398 @default.
• W1970742783 hasAuthorship W1970742783A5063242540 @default.
• W1970742783 hasAuthorship W1970742783A5069057400 @default.
• W1970742783 hasAuthorship W1970742783A5079681801 @default.
• W1970742783 hasConcept C105339364 @default.
• W1970742783 hasConcept C111919701 @default.
• W1970742783 hasConcept C117214928 @default.
• W1970742783 hasConcept C144796933 @default.
• W1970742783 hasConcept C159047783 @default.
• W1970742783 hasConcept C159985019 @default.
• W1970742783 hasConcept C171250308 @default.
• W1970742783 hasConcept C192562407 @default.
• W1970742783 hasConcept C197746943 @default.
• W1970742783 hasConcept C2779820397 @default.
• W1970742783 hasConcept C2908647359 @default.
• W1970742783 hasConcept C2986740045 @default.
• W1970742783 hasConcept C3013748606 @default.
• W1970742783 hasConcept C41008148 @default.
• W1970742783 hasConcept C521977710 @default.
• W1970742783 hasConcept C71924100 @default.
• W1970742783 hasConcept C97228660 @default.
• W1970742783 hasConcept C99454951 @default.
• W1970742783 hasConceptScore W1970742783C105339364 @default.
• W1970742783 hasConceptScore W1970742783C111919701 @default.
• W1970742783 hasConceptScore W1970742783C117214928 @default.

• next