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- W1971036505 abstract "Abstract A sensitive method for simultaneous determination of azithromycin (AZI), acetylspiramycin (ACE), erythromycin (ERY), and josamycin (JOS) was developed by CE coupled with electrochemiluminescence detection with Ru(bpy) 3 2+ . The parameters related to separation and detection were investigated in detail. The four macrolides were well separated and detected within 6 min under the optimized conditions. The LOD ( S / N =3) of AZI, ACE, ERY, and JOS were 1.2×10 −9 , 7.1×10 −9 , 3.9×10 −8 and 9.5×10 −8 mol/L, respectively. The LOQ ( S / N =10) of AZI, ACE, ERY, and JOS in human urine were 8.2×10 −8 , 2.5×10 −7 , 8.9×10 −7 and 1.2×10 −6 mol/L, respectively. The recoveries of the four macrolides in human urine and pharmaceutical tablet samples were 85.0–104.0% at different concentration levels." @default.
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- W1971036505 date "2010-01-01" @default.
- W1971036505 modified "2023-10-12" @default.
- W1971036505 title "A sensitive method for simultaneous determination of four macrolides by CE with electrochemiluminescence detection and its applications in human urine and tablets" @default.
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- W1971036505 doi "https://doi.org/10.1002/elps.200900302" @default.
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