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• W1973281036 abstract "Maintenance therapy of drug-addict mothers with medical and psychosocial support may reduce complications (prematurity, growth retardation, fetal distress and fetal death). Methadone has been widely used during pregnancy with beneficial effects. Buprenorphine (BUP) is used more and more and shows the same beneficial effects.Twenty-four pregnant women received BUP and their infants were enrolled in the study. Thirteen retrospective (GI) and 11 prospective (GII) cases were studied. In the GII, the women were treated and followed up in an interdisciplinary manner.Complications in GII were less frequent than in GI: 9 vs 30% of prematurity, 9 vs 46% of fetal growth retardation and 0 vs 23% of acute fetal distress. However, the frequency of withdrawal syndrome was the same in both groups, 63 vs 69%, though improvements came more rapidly in GII.This study shows that the use of BUP during pregnancy, combined with medical and psychosocial support, may reduce addiction complications. This support has to be maintained after the birth." @default.
• W1973281036 created "2016-06-24" @default.
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• W1973281036 date "1999-11-01" @default.
• W1973281036 modified "2023-10-16" @default.
• W1973281036 title "Grossesse et buprénorphine. À propos de 24 cas" @default.
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• W1973281036 doi "https://doi.org/10.1016/s0929-693x(00)86300-9" @default.
• W1973281036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10587741" @default.
• W1973281036 hasPublicationYear "1999" @default.
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