FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1975936699> ?p ?o ?g. }

• W1975936699 endingPage "4912" @default.
• W1975936699 startingPage "4909" @default.
• W1975936699 abstract "One of the most important, yet elusive, aspects of the protein folding question lies in the nature of the transition state. Direct information about the structural properties of the transition state can be obtained from determination of the activation volumes for the folding and unfolding transitions. The present pressure-jump relaxation study on the folding/unfolding of staphylococcal nuclease reveals that the volume of the protein-solvent system is larger in the transition state than in either the folded or unfolded states. Moreover, the activation volume of folding is much larger than that of unfolding. These results support a molten globule-like model for the transition state of nuclease in which the polypeptide chain is in a collapsed, loosely packed, solvent-excluded structure. In this model, hydrophobic collapse with concomitant desolvation is the rate-limiting step in the folding of the polypeptide chain, and solvent-excluded expansion of the folded state is the rate-limiting step in protein unfolding." @default.
• W1975936699 created "2016-06-24" @default.
• W1975936699 creator A5001861589 @default.
• W1975936699 creator A5059359201 @default.
• W1975936699 creator A5068651734 @default.
• W1975936699 date "1995-04-18" @default.
• W1975936699 modified "2023-10-14" @default.
• W1975936699 title "Evidence for a molten globule-like transition state in protein folding from determination of activation volumes" @default.
• W1975936699 cites W1964592445 @default.
• W1975936699 cites W1967542371 @default.
• W1975936699 cites W1974326790 @default.
• W1975936699 cites W1988787136 @default.
• W1975936699 cites W1993067577 @default.
• W1975936699 cites W2006712775 @default.
• W1975936699 cites W2025240528 @default.
• W1975936699 cites W2029141945 @default.
• W1975936699 cites W2036130605 @default.
• W1975936699 cites W2036509474 @default.
• W1975936699 cites W2040655080 @default.
• W1975936699 cites W2043605544 @default.
• W1975936699 cites W2054632829 @default.
• W1975936699 cites W2065367764 @default.
• W1975936699 cites W2088533660 @default.
• W1975936699 cites W2111726538 @default.
• W1975936699 cites W2171414493 @default.
• W1975936699 doi "https://doi.org/10.1021/bi00015a001" @default.
• W1975936699 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7711012" @default.
• W1975936699 hasPublicationYear "1995" @default.
• W1975936699 type Work @default.
• W1975936699 sameAs 1975936699 @default.
• W1975936699 citedByCount "163" @default.
• W1975936699 countsByYear W19759366992012 @default.
• W1975936699 countsByYear W19759366992013 @default.
• W1975936699 countsByYear W19759366992014 @default.
• W1975936699 countsByYear W19759366992015 @default.
• W1975936699 countsByYear W19759366992016 @default.
• W1975936699 countsByYear W19759366992017 @default.
• W1975936699 countsByYear W19759366992018 @default.
• W1975936699 countsByYear W19759366992019 @default.
• W1975936699 countsByYear W19759366992020 @default.
• W1975936699 countsByYear W19759366992021 @default.
• W1975936699 countsByYear W19759366992022 @default.
• W1975936699 countsByYear W19759366992023 @default.
• W1975936699 crossrefType "journal-article" @default.
• W1975936699 hasAuthorship W1975936699A5001861589 @default.
• W1975936699 hasAuthorship W1975936699A5059359201 @default.
• W1975936699 hasAuthorship W1975936699A5068651734 @default.
• W1975936699 hasConcept C118493188 @default.
• W1975936699 hasConcept C119599485 @default.
• W1975936699 hasConcept C121332964 @default.
• W1975936699 hasConcept C127413603 @default.
• W1975936699 hasConcept C15744967 @default.
• W1975936699 hasConcept C159467904 @default.
• W1975936699 hasConcept C162203774 @default.
• W1975936699 hasConcept C174507519 @default.
• W1975936699 hasConcept C178790620 @default.
• W1975936699 hasConcept C185592680 @default.
• W1975936699 hasConcept C188198153 @default.
• W1975936699 hasConcept C19472624 @default.
• W1975936699 hasConcept C204328495 @default.
• W1975936699 hasConcept C206276672 @default.
• W1975936699 hasConcept C2776029896 @default.
• W1975936699 hasConcept C2776545253 @default.
• W1975936699 hasConcept C2780471494 @default.
• W1975936699 hasConcept C46449900 @default.
• W1975936699 hasConcept C55493867 @default.
• W1975936699 hasConcept C77805123 @default.
• W1975936699 hasConcept C78519656 @default.
• W1975936699 hasConcept C8010536 @default.
• W1975936699 hasConcept C97355855 @default.
• W1975936699 hasConceptScore W1975936699C118493188 @default.
• W1975936699 hasConceptScore W1975936699C119599485 @default.
• W1975936699 hasConceptScore W1975936699C121332964 @default.
• W1975936699 hasConceptScore W1975936699C127413603 @default.
• W1975936699 hasConceptScore W1975936699C15744967 @default.
• W1975936699 hasConceptScore W1975936699C159467904 @default.
• W1975936699 hasConceptScore W1975936699C162203774 @default.
• W1975936699 hasConceptScore W1975936699C174507519 @default.
• W1975936699 hasConceptScore W1975936699C178790620 @default.
• W1975936699 hasConceptScore W1975936699C185592680 @default.
• W1975936699 hasConceptScore W1975936699C188198153 @default.
• W1975936699 hasConceptScore W1975936699C19472624 @default.
• W1975936699 hasConceptScore W1975936699C204328495 @default.
• W1975936699 hasConceptScore W1975936699C206276672 @default.
• W1975936699 hasConceptScore W1975936699C2776029896 @default.
• W1975936699 hasConceptScore W1975936699C2776545253 @default.
• W1975936699 hasConceptScore W1975936699C2780471494 @default.
• W1975936699 hasConceptScore W1975936699C46449900 @default.
• W1975936699 hasConceptScore W1975936699C55493867 @default.
• W1975936699 hasConceptScore W1975936699C77805123 @default.
• W1975936699 hasConceptScore W1975936699C78519656 @default.
• W1975936699 hasConceptScore W1975936699C8010536 @default.
• W1975936699 hasConceptScore W1975936699C97355855 @default.
• W1975936699 hasIssue "15" @default.
• W1975936699 hasLocation W19759366991 @default.
• W1975936699 hasLocation W19759366992 @default.
• W1975936699 hasOpenAccess W1975936699 @default.
• W1975936699 hasPrimaryLocation W19759366991 @default.

• next