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• W1981036614 abstract "The posterior cingulate and the medial parietal cortices constitute an ensemble known as the posteromedial cortex (PMC), which consists of Brodmann areas 23, 29, 30, 31, and 7m. To understand the neural relationship of the PMC with the rest of the brain, we injected its component areas with four different anterograde and retrograde tracers in the cynomolgus monkey and found that all PMC areas are interconnected with each other and with the anterior cingulate, the mid-dorsolateral prefrontal, the lateral parietal cortices, and area TPO, as well as the thalamus, where projections from some of the PMC areas traverse in an uninterrupted bar-like manner, the dorsum of this structure from the posteriormost nuclei to its rostralmost tip. All PMC regions also receive projections from the claustrum and the basal forebrain and project to the caudate, the basis pontis, and the zona incerta. Moreover, the posterior cingulate areas are interconnected with the parahippocampal regions, whereas the medial parietal cortex projects only sparsely to the presubiculum. Although local interconnections and shared remote connections of all PMC components suggest a functional relationship among them, the distinct connections of each area with different neural structures suggests that distinct functional modules may be operating within the PMC. Our study provides a large-scale map of the PMC connections with the rest of the brain, which may serve as a useful tool for future studies of this cortical region and may contribute to elucidating its intriguing pattern of activity seen in recent functional imaging studies." @default.
• W1981036614 created "2016-06-24" @default.
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• W1981036614 creator A5059660895 @default.
• W1981036614 creator A5070506273 @default.
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• W1981036614 date "2006-01-23" @default.
• W1981036614 modified "2023-09-29" @default.
• W1981036614 title "Neural connections of the posteromedial cortex in the macaque" @default.
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• W1981036614 doi "https://doi.org/10.1073/pnas.0507729103" @default.
• W1981036614 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1345704" @default.
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