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- W1981306999 abstract "This paper is concerned with the integration of a heat and mass model with a population balance model of a fluid bed granulation process. The heat/mass model helps to track the liquid and porosity changes that occur within the granulation process due to simultaneous drying in the granulator. A mechanistic kernel proposed by [22] was used to model the aggregation process, which is a function of mechanistic properties such as liquid thickness and particle size. The model takes into account various mechanisms that significantly affect the granulation outcome, such as aggregation, drying/rewetting, and consolidation. Since these rate processes evolve dynamically, the aggregation kernel is updated periodically over time and for the first time, dynamically coupled with the heat/mass model to provide a more accurate qualitative description of granulation dynamics in a fluid-bed granulator." @default.
- W1981306999 created "2016-06-24" @default.
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- W1981306999 date "2013-01-01" @default.
- W1981306999 modified "2023-09-30" @default.
- W1981306999 title "Multi-dimensional mechanistic modeling of fluid bed granulation processes: An integrated approach" @default.
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- W1981306999 doi "https://doi.org/10.1016/j.apt.2012.03.005" @default.
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